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| Nomenclature |
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Symbol:
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Alx1tm1Crm
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Name:
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ALX homeobox 1;
targeted mutation 1, Benoit de Crombrugghe
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MGI ID: |
MGI:1857553 |
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Synonyms: |
Cart1- |
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Gene:
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Alx1
Location:
Chr10:103007847-103029051 bp, - strand
Genetic Position: Chr10,
53.56 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:33716
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced a 7.4kb genomic fragment containing exons 1-3. These sequences encode two thirds of the protein including the homeodomain and the potential translation initiation site. (J:33716)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Alx1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:33716
Zhao Q et al.,
"Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene."
Nat Genet 1996 Jul;13(3):275-83
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All: |
3 reference(s)
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Analysis Tools
