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| Nomenclature |
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Symbol:
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Cxcr2tm1Mwm
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Name:
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chemokine (C-X-C motif) receptor 2;
targeted mutation 1, Mark Moore
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MGI ID: |
MGI:1857153 |
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Synonyms: |
Cmkar2tm1Mwm, Cmkartm1Mwm, CXCR-, CXCR2 -, CXCR2-, Il8rbtm1Mwm, mCXCR-, mCXCR2-, mIL-8Rh-, mIL-8Rh KO |
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Gene:
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Cxcr2
Location:
Chr1:74153989-74161238 bp, + strand
Genetic Position: Chr1,
38.41 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:19570
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A neomycin selection cassette replaced the entire coding sequence of the gene. (J:19570)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:19570
Cacalano G et al.,
"Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog."
Science 1994 Jul 29;265(5172):682-4
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All: |
93 reference(s)
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