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Cxcr2tm1Mwm
Targeted Allele Detail

Nomenclature
Symbol: Cxcr2tm1Mwm
Name: chemokine (C-X-C motif) receptor 2; targeted mutation 1, Mark Moore
MGI ID: MGI:1857153
Synonyms: Cmkar2tm1Mwm, Cmkartm1Mwm, CXCR-, CXCR2 -, CXCR2-, Il8rbtm1Mwm, mCXCR-, mCXCR2-, mIL-8Rh-, mIL-8Rh KO
Gene: Cxcr2   Location: Chr1:74153989-74161238 bp, + strand    Genetic Position: Chr1, 38.41 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:19570
Parent Cell Line: D3 (ES Cell)
Strain of Origin: 129S2/SvPas
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    A neomycin selection cassette replaced the entire coding sequence of the gene. (J:19570)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cxcr2 Mutation: 7 strains or lines available
References
Original: J:19570 Cacalano G et al., "Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog." Science 1994 Jul 29;265(5172):682-4
All: 93 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory