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| Nomenclature |
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Symbol:
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Lama2dy
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Name:
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laminin, alpha 2;
dystrophia muscularis
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MGI ID: |
MGI:1856026 |
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Synonyms: |
dy |
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Gene:
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Lama2
Location:
Chr10:26981288-27616942 bp, - strand
Genetic Position: Chr10,
14.23 cM, cytoband A4-B1
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Lama2dy/Lama2dy and control
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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129P1/Re
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Undefined |
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Mutation details: Analysis of Lama2 expression of dystrophic dy mice revealed a specific deficiency of this mRNA in skeletal muscle, cardiac muscle, and peripheral nerve. (J:18187, J:44989)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
This mutation arose spontaneously in the 129/Re inbred strain at The Jackson Laboratory in 1951.
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| References |
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Original: |
J:13125
Michelson AM et al.,
"Dystrophia muscularis: a hereditary primary myopathy in the house mouse."
Proc Natl Acad Sci U S A 1955 Dec 15;41(12):1079-1084
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All: |
64 reference(s)
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Analysis Tools
