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GO Annotations Graph
thioredoxin 1

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0019899enzyme bindingISOJ:155856
Molecular FunctionGO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptorIBAJ:161428
Molecular FunctionGO:0015037peptide disulfide oxidoreductase activityIDAJ:138150
Molecular FunctionGO:0044822poly(A) RNA bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:138150
Molecular FunctionGO:0015035protein disulfide oxidoreductase activityIBAJ:161428
Cellular ComponentGO:0030424axonISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:74095
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005829cytosolIDAJ:138150
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0030425dendriteISOJ:155856
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005739mitochondrionIDAJ:86816
Cellular ComponentGO:0005739mitochondrionIDAJ:151002
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:138150
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:74095
Biological ProcessGO:0045454cell redox homeostasisIDAJ:138150
Biological ProcessGO:0034599cellular response to oxidative stressIBAJ:161428
Biological ProcessGO:0006662glycerol ether metabolic processIEAJ:72247
Biological ProcessGO:1903206negative regulation of hydrogen peroxide-induced cell deathISOJ:164563
Biological ProcessGO:0046826negative regulation of protein export from nucleusIDAJ:138150
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIGIJ:138150
Biological ProcessGO:0055114oxidation-reduction processIBAJ:161428
Biological ProcessGO:0055114oxidation-reduction processISOJ:164563
Biological ProcessGO:0043388positive regulation of DNA bindingISOJ:164563
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:0006457protein foldingIBAJ:161428
Biological ProcessGO:0033158regulation of protein import into nucleus, translocationISOJ:164563
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0009314response to radiationISOJ:164563
Biological ProcessGO:0000103sulfate assimilationIBAJ:161428
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0006810transportIEAJ:60000

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.02
The Jackson Laboratory