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GO Annotations Graph
 Symbol
Name
ID
Trf
transferrin
MGI:98821

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Fri Jan 17 13:56:29 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0008199ferric iron bindingISOJ:155856
Molecular FunctionGO:0015091ferric iron transmembrane transporter activityISOJ:155856
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:193640
Cellular ComponentGO:0016324apical plasma membraneISOJ:164563
Cellular ComponentGO:0045178basal part of cellISOJ:164563
Cellular ComponentGO:0009925basal plasma membraneISOJ:164563
Cellular ComponentGO:0005604basement membraneISOJ:155856
Cellular ComponentGO:0005905coated pitIDAJ:164083
Cellular ComponentGO:0005905coated pitISOJ:164563
Cellular ComponentGO:0016023cytoplasmic membrane-bounded vesicleISOJ:164563
Cellular ComponentGO:0097433dense bodyISOJ:170947
Cellular ComponentGO:0005769early endosomeISOJ:164563
Cellular ComponentGO:0005769early endosomeIDAJ:198162
Cellular ComponentGO:0030139endocytic vesicleIDAJ:80735
Cellular ComponentGO:0030139endocytic vesicleISOJ:92184
Cellular ComponentGO:0030139endocytic vesicleISOJ:94651
Cellular ComponentGO:0005768endosomeIDAJ:93351
Cellular ComponentGO:0005768endosomeIDAJ:103440
Cellular ComponentGO:0005768endosomeIDAJ:135168
Cellular ComponentGO:0005768endosomeIDAJ:198162
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005576extracellular regionIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0005770late endosomeISOJ:164563
Cellular ComponentGO:0005739mitochondrionISOJ:164563
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:164563
Cellular ComponentGO:0055037recycling endosomeIDAJ:115416
Cellular ComponentGO:0055037recycling endosomeIDAJ:142909
Cellular ComponentGO:0055037recycling endosomeISOJ:164563
Cellular ComponentGO:0030120vesicle coatISOJ:189648
Biological ProcessGO:0007015actin filament organizationIDAJ:146763
Biological ProcessGO:0007257activation of JUN kinase activityIDAJ:146763
Biological ProcessGO:0006879cellular iron ion homeostasisIEAJ:72247
Biological ProcessGO:0070371ERK1 and ERK2 cascadeIDAJ:146763
Biological ProcessGO:0015682ferric iron transportISOJ:155856
Biological ProcessGO:0006811ion transportIEAJ:60000
Biological ProcessGO:0055072iron ion homeostasisIEAJ:60000
Biological ProcessGO:0034755iron ion transmembrane transportISOJ:155856
Biological ProcessGO:0006826iron ion transportIMPJ:82711
Biological ProcessGO:0030316osteoclast differentiationIDAJ:146763
Biological ProcessGO:0045780positive regulation of bone resorptionIDAJ:146763
Biological ProcessGO:2000147positive regulation of cell motilityIDAJ:146763
Biological ProcessGO:0031643positive regulation of myelinationISOJ:155856
Biological ProcessGO:0070447positive regulation of oligodendrocyte progenitor proliferationISOJ:155856
Biological ProcessGO:0042327positive regulation of phosphorylationIDAJ:146763
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:146763
Biological ProcessGO:0060395SMAD protein signal transductionIDAJ:45399
Biological ProcessGO:0006810transportIEAJ:60000

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory