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GO Annotations Graph

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0019899enzyme bindingISOJ:164563
Molecular FunctionGO:0042826histone deacetylase bindingISOJ:164563
Molecular FunctionGO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activityIDAJ:140901
Molecular FunctionGO:0044212transcription regulatory region DNA bindingISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0070062extracellular vesicular exosomeISOJ:164563
Cellular ComponentGO:0031315extrinsic component of mitochondrial outer membraneISOJ:155856
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0030061mitochondrial cristaISOJ:155856
Cellular ComponentGO:0005743mitochondrial inner membraneIDAJ:100953
Cellular ComponentGO:0005739mitochondrionIDAJ:86816
Cellular ComponentGO:0005739mitochondrionIDAJ:129870
Cellular ComponentGO:0005739mitochondrionIDAJ:131696
Cellular ComponentGO:0005739mitochondrionIDAJ:151002
Cellular ComponentGO:0005739mitochondrionISOJ:155856
Cellular ComponentGO:0005739mitochondrionISOJ:164563
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:140901
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusISOJ:164563
Biological ProcessGO:0071354cellular response to interleukin-6ISOJ:164563
Biological ProcessGO:0071897DNA biosynthetic processIMPJ:140901
Biological ProcessGO:0006260DNA replicationIEAJ:60000
Biological ProcessGO:0016575histone deacetylationISOJ:164563
Biological ProcessGO:0060766negative regulation of androgen receptor signaling pathwayISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:155856
Biological ProcessGO:0030308negative regulation of cell growthISOJ:164563
Biological ProcessGO:0008285negative regulation of cell proliferationISOJ:155856
Biological ProcessGO:0008285negative regulation of cell proliferationISOJ:164563
Biological ProcessGO:2000323negative regulation of glucocorticoid receptor signaling pathwayISOJ:164563
Biological ProcessGO:0010944negative regulation of transcription by competitive promoter bindingISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIDAJ:140901
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0001649osteoblast differentiationISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0050847progesterone receptor signaling pathwayISOJ:164563
Biological ProcessGO:0006355regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0006366transcription from RNA polymerase II promoterIDAJ:140901

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.22
The Jackson Laboratory