GO Annotations Graph

Symbol
Name
ID

Pax6
paired box gene 6
MGI:97490

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph is also available as SVG.
Graph generated Tue Sep 11 15:01:59 2012.

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003680	AT DNA binding	ISO	J:155856
Molecular Function	GO:0070410	co-SMAD binding	IDA	J:172985
Molecular Function	GO:0003677	DNA binding	IDA	J:83532
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0035035	histone acetyltransferase binding	IDA	MGI:5306308
Molecular Function	GO:0071837	HMG box domain binding	IPI	J:175179
Molecular Function	GO:0005515	protein binding	IPI	J:114731
Molecular Function	GO:0005515	protein binding	IPI	J:114731
Molecular Function	GO:0019901	protein kinase binding	IPI	MGI:5306308
Molecular Function	GO:0070412	R-SMAD binding	IDA	J:172985
Molecular Function	GO:0070412	R-SMAD binding	ISO	J:164563
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	IDA	MGI:5306308
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	IDA	J:170025
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	IDA	J:170025
Molecular Function	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	IDA	MGI:5306308
Molecular Function	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	sequence-specific DNA binding transcription factor activity	TAS	J:54357
Molecular Function	GO:0003700	sequence-specific DNA binding transcription factor activity	IDA	J:133921
Molecular Function	GO:0008134	transcription factor binding	IPI	MGI:5306308
Molecular Function	GO:0044212	transcription regulatory region DNA binding	IDA	J:149737
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:137611
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005622	intracellular	IDA	J:113146
Cellular Component	GO:0044424	intracellular part	IDA	J:105207
Cellular Component	GO:0044424	intracellular part	IDA	J:120581
Cellular Component	GO:0000790	nuclear chromatin	IDA	J:170025
Cellular Component	GO:0000790	nuclear chromatin	ISO	J:155856
Cellular Component	GO:0000790	nuclear chromatin	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:77680
Cellular Component	GO:0005634	nucleus	IDA	J:86636
Cellular Component	GO:0005634	nucleus	IDA	J:109412
Cellular Component	GO:0005634	nucleus	IDA	J:74097
Cellular Component	GO:0005634	nucleus	IDA	J:41620
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:150768
Cellular Component	GO:0005667	transcription factor complex	TAS	J:54357
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:78745
Biological Process	GO:0009952	anterior/posterior pattern specification	IGI	J:98539
Biological Process	GO:0048708	astrocyte differentiation	IMP	J:147382
Biological Process	GO:0007411	axon guidance	IMP	J:86369
Biological Process	GO:0007411	axon guidance	IMP	J:76341
Biological Process	GO:0007409	axonogenesis	IMP	J:94588
Biological Process	GO:0001568	blood vessel development	ISO	J:164563
Biological Process	GO:0007420	brain development	IMP	J:54722
Biological Process	GO:0007420	brain development	IMP	J:78745
Biological Process	GO:0007420	brain development	ISO	J:155856
Biological Process	GO:0043010	camera-type eye development	IMP	J:65765
Biological Process	GO:0043010	camera-type eye development	IGI	J:78468
Biological Process	GO:0043010	camera-type eye development	IMP	J:83532
Biological Process	GO:0043010	camera-type eye development	IGI	J:77351
Biological Process	GO:0043010	camera-type eye development	IMP	J:82632
Biological Process	GO:0043010	camera-type eye development	IMP	J:66649
Biological Process	GO:0043010	camera-type eye development	IMP	J:99962
Biological Process	GO:0030154	cell differentiation	IMP	J:92173
Biological Process	GO:0045165	cell fate commitment	IGI	J:93057
Biological Process	GO:0045165	cell fate commitment	IMP	J:99239
Biological Process	GO:0001709	cell fate determination	IMP	J:83532
Biological Process	GO:0021796	cerebral cortex regionalization	IMP	J:102092
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	IMP	J:66590
Biological Process	GO:0061303	cornea development in camera-type eye	ISO	J:164563
Biological Process	GO:0009950	dorsal/ventral axis specification	IMP	J:58952
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:94457
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:99239
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	IGI	J:139006
Biological Process	GO:0042462	eye photoreceptor cell development	IMP	J:82632
Biological Process	GO:0021797	forebrain anterior/posterior pattern specification	IMP	J:41030
Biological Process	GO:0030900	forebrain development	IMP	J:94457
Biological Process	GO:0030900	forebrain development	IMP	J:94588
Biological Process	GO:0030900	forebrain development	IMP	J:98620
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	IMP	J:66590
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	IMP	J:65195
Biological Process	GO:0021905	forebrain-midbrain boundary formation	IMP	J:41030
Biological Process	GO:0042593	glucose homeostasis	ISO	J:164563
Biological Process	GO:0030902	hindbrain development	ISO	J:155856
Biological Process	GO:0061072	iris morphogenesis	ISO	J:164563
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:99962
Biological Process	GO:0032808	lacrimal gland development	IMP	J:62162
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:21950
Biological Process	GO:0007275	multicellular organismal development	IEA	J:60000
Biological Process	GO:0008285	negative regulation of cell proliferation	IMP	J:94457
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:99962
Biological Process	GO:0045665	negative regulation of neuron differentiation	IGI	J:112802
Biological Process	GO:0001764	neuron migration	IMP	J:98620
Biological Process	GO:0001764	neuron migration	ISO	J:155856
Biological Process	GO:0021778	oligodendrocyte cell fate specification	IMP	J:50974
Biological Process	GO:0021543	pallium development	IMP	J:66590
Biological Process	GO:0003322	pancreatic A cell development	IMP	J:170025
Biological Process	GO:0003322	pancreatic A cell development	ISO	J:155856
Biological Process	GO:0003322	pancreatic A cell development	ISO	J:164563
Biological Process	GO:0021983	pituitary gland development	IMP	J:58952
Biological Process	GO:0042660	positive regulation of cell fate specification	ISO	J:155856
Biological Process	GO:0030858	positive regulation of epithelial cell differentiation	IMP	J:99962
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:170025
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	IMP	J:133921
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IDA	J:98488
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IDA	J:133921
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IDA	J:154645
Biological Process	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IDA	MGI:5306308
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	IDA	J:170025
Biological Process	GO:0045893	positive regulation of transcription, DNA-dependent	ISO	J:164563
Biological Process	GO:0033365	protein localization to organelle	IMP	J:103131
Biological Process	GO:0030334	regulation of cell migration	IMP	J:54722
Biological Process	GO:0050678	regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0010468	regulation of gene expression	IMP	J:116586
Biological Process	GO:0010468	regulation of gene expression	IMP	J:142755
Biological Process	GO:0010468	regulation of gene expression	IMP	J:102092
Biological Process	GO:0050767	regulation of neurogenesis	IMP	J:94457
Biological Process	GO:0050767	regulation of neurogenesis	ISO	J:155856
Biological Process	GO:0045664	regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0048505	regulation of timing of cell differentiation	IMP	J:50974
Biological Process	GO:0006357	regulation of transcription from RNA polymerase II promoter	IMP	J:149737
Biological Process	GO:0006357	regulation of transcription from RNA polymerase II promoter	ISO	J:164563
Biological Process	GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	IMP	J:41620
Biological Process	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	IMP	J:41620
Biological Process	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	IMP	J:41620
Biological Process	GO:0006355	regulation of transcription, DNA-dependent	TAS	J:54357
Biological Process	GO:0007435	salivary gland morphogenesis	IMP	J:74539
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0007224	smoothened signaling pathway	IDA	J:138713
Biological Process	GO:0006366	transcription from RNA polymerase II promoter	IMP	J:170025
Biological Process	GO:0006366	transcription from RNA polymerase II promoter	ISO	J:155856
Biological Process	GO:0006366	transcription from RNA polymerase II promoter	ISO	J:164563
Biological Process	GO:0006351	transcription, DNA-dependent	IEA	J:60000

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IAS Inferred from ancestral seqeuence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IKR Inferred from key residues

IMP Inferred from mutant phenotype

IMR Inferred from missing residues

IPI Inferred from physical interaction

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Obsolete Evidence Code: Not Recorded

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 04/03/2013 MGI 5.12