About   Help   FAQ
GO Annotations Graph
 Symbol
Name
ID
Nos2
nitric oxide synthase 2, inducible
MGI:97361

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003779actin bindingISOJ:155856
Molecular FunctionGO:0034618arginine bindingIDAJ:139344
Molecular FunctionGO:0008013beta-catenin bindingISOJ:155856
Molecular FunctionGO:0045296cadherin bindingISOJ:155856
Molecular FunctionGO:0005516calmodulin bindingTASJ:113936
Molecular FunctionGO:0008603cAMP-dependent protein kinase regulator activityISOJ:155856
Molecular FunctionGO:0050660flavin adenine dinucleotide bindingIDAJ:139347
Molecular FunctionGO:0010181FMN bindingIDAJ:139347
Molecular FunctionGO:0020037heme bindingIDAJ:139344
Molecular FunctionGO:0020037heme bindingIDAJ:139347
Molecular FunctionGO:0051879Hsp90 protein bindingISOJ:155856
Molecular FunctionGO:0005506iron ion bindingIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0050661NADP bindingIEAJ:72247
Molecular FunctionGO:0003958NADPH-hemoprotein reductase activityIBAJ:161428
Molecular FunctionGO:0004517nitric-oxide synthase activityIDAJ:139344
Molecular FunctionGO:0004517nitric-oxide synthase activityIDAJ:139347
Molecular FunctionGO:0004517nitric-oxide synthase activityISOJ:155856
Molecular FunctionGO:0004517nitric-oxide synthase activityISOJ:164563
Molecular FunctionGO:0050998nitric-oxide synthase bindingISOJ:155856
Molecular FunctionGO:0016491oxidoreductase activityIEAJ:60000
Molecular FunctionGO:0016491oxidoreductase activityIEAJ:72247
Molecular FunctionGO:0005515protein bindingIPIJ:85387
Molecular FunctionGO:0005515protein bindingIPIJ:113936
Molecular FunctionGO:0005515protein bindingIPIJ:113936
Molecular FunctionGO:0005515protein bindingIPIJ:168203
Molecular FunctionGO:0005515protein bindingIPIJ:169889
Molecular FunctionGO:0042803protein homodimerization activityIDAJ:139344
Molecular FunctionGO:0042803protein homodimerization activityISOJ:155856
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0005102receptor bindingISOJ:164563
Molecular FunctionGO:0034617tetrahydrobiopterin bindingIDAJ:139344
Cellular ComponentGO:0030863cortical cytoskeletonIDAJ:85387
Cellular ComponentGO:0005737cytoplasmIDAJ:74206
Cellular ComponentGO:0005737cytoplasmIDAJ:85387
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005829cytosolTASJ:113936
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0005622intracellularIBAJ:161428
Cellular ComponentGO:0005622intracellularISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0048471perinuclear region of cytoplasmIDAJ:85387
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:155856
Cellular ComponentGO:0005777peroxisomeISOJ:155856
Cellular ComponentGO:0005777peroxisomeISOJ:164563
Cellular ComponentGO:0012506vesicle membraneISOJ:155856
Biological ProcessGO:0006527arginine catabolic processIDAJ:139347
Biological ProcessGO:0006527arginine catabolic processISOJ:164563
Biological ProcessGO:0071346cellular response to interferon-gammaIDAJ:155210
Biological ProcessGO:0071222cellular response to lipopolysaccharideIDAJ:142604
Biological ProcessGO:0071222cellular response to lipopolysaccharideIDAJ:155210
Biological ProcessGO:0042742defense response to bacteriumIMPJ:85213
Biological ProcessGO:0042742defense response to bacteriumISOJ:164563
Biological ProcessGO:0006954inflammatory responseTASJ:113936
Biological ProcessGO:0045776negative regulation of blood pressureIBAJ:161428
Biological ProcessGO:0010629negative regulation of gene expressionISOJ:164563
Biological ProcessGO:0010629negative regulation of gene expressionIGIJ:183976
Biological ProcessGO:0042177negative regulation of protein catabolic processIDAJ:169889
Biological ProcessGO:0006809nitric oxide biosynthetic processIDAJ:139344
Biological ProcessGO:0006809nitric oxide biosynthetic processIDAJ:139347
Biological ProcessGO:0006809nitric oxide biosynthetic processISOJ:164563
Biological ProcessGO:0007263nitric oxide mediated signal transductionIBAJ:161428
Biological ProcessGO:0055114oxidation-reduction processIBAJ:161428
Biological ProcessGO:0018119peptidyl-cysteine S-nitrosylationIDAJ:168203
Biological ProcessGO:0031284positive regulation of guanylate cyclase activityIBAJ:161428
Biological ProcessGO:0051712positive regulation of killing of cells of other organismISOJ:164563
Biological ProcessGO:0045909positive regulation of vasodilationIBAJ:161428
Biological ProcessGO:0042127regulation of cell proliferationIGIJ:72030
Biological ProcessGO:0042127regulation of cell proliferationIGIJ:73152
Biological ProcessGO:0050796regulation of insulin secretionISOJ:164563
Biological ProcessGO:0045859regulation of protein kinase activityISOJ:155856
Biological ProcessGO:0001666response to hypoxiaIDAJ:85387
Biological ProcessGO:0032496response to lipopolysaccharideIDAJ:180997
Biological ProcessGO:0006801superoxide metabolic processIMPJ:85213

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory