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GO Annotations Graph
IL2 inducible T cell kinase

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0004715non-membrane spanning protein tyrosine kinase activityIBAJ:161428
Molecular FunctionGO:0004715non-membrane spanning protein tyrosine kinase activityISOJ:164563
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:151074
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:60000
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005911cell-cell junctionIDAJ:205441
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0031234extrinsic component of cytoplasmic side of plasma membraneIBAJ:161428
Biological ProcessGO:0007202activation of phospholipase C activityIMPJ:54449
Biological ProcessGO:0002250adaptive immune responseIMPJ:54449
Biological ProcessGO:0001816cytokine productionIMPJ:54449
Biological ProcessGO:0002376immune system processIEAJ:60000
Biological ProcessGO:0045087innate immune responseIBAJ:161428
Biological ProcessGO:0032609interferon-gamma productionIGIJ:131540
Biological ProcessGO:0032609interferon-gamma productionIMPJ:131540
Biological ProcessGO:0032633interleukin-4 productionIGIJ:131540
Biological ProcessGO:0032633interleukin-4 productionIMPJ:131540
Biological ProcessGO:0035556intracellular signal transductionIEAJ:72247
Biological ProcessGO:0001865NK T cell differentiationIGIJ:131540
Biological ProcessGO:0001865NK T cell differentiationIMPJ:131540
Biological ProcessGO:0038083peptidyl-tyrosine autophosphorylationIBAJ:161428
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0042127regulation of cell proliferationIBAJ:161428
Biological ProcessGO:0050852T cell receptor signaling pathwayIMPJ:54449
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayIBAJ:161428

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.02
The Jackson Laboratory