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GO Annotations Graph
insulin-like growth factor 2

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0008083growth factor activityISOJ:164563
Molecular FunctionGO:0005179hormone activityIEAJ:60000
Molecular FunctionGO:0005179hormone activityIEAJ:72247
Molecular FunctionGO:0005158insulin receptor bindingISOJ:164563
Molecular FunctionGO:0005159insulin-like growth factor receptor bindingIPIJ:86296
Molecular FunctionGO:0005159insulin-like growth factor receptor bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:156975
Molecular FunctionGO:0005515protein bindingIPIJ:86296
Molecular FunctionGO:0043539protein serine/threonine kinase activator activityIMPJ:158405
Molecular FunctionGO:0030546receptor activator activityIMPJ:158405
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005576extracellular regionIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceIDAJ:138783
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Biological ProcessGO:0005975carbohydrate metabolic processIEAJ:60000
Biological ProcessGO:0031017exocrine pancreas developmentIMPJ:79280
Biological ProcessGO:0006006glucose metabolic processIEAJ:60000
Biological ProcessGO:0038028insulin receptor signaling pathway via phosphatidylinositol 3-kinaseIMPJ:158405
Biological ProcessGO:0007613memoryISOJ:155856
Biological ProcessGO:0045953negative regulation of natural killer cell mediated cytotoxicityISOJ:155856
Biological ProcessGO:0009887organ morphogenesisIMPJ:79280
Biological ProcessGO:0001503ossificationIEAJ:60000
Biological ProcessGO:0042104positive regulation of activated T cell proliferationISOJ:164563
Biological ProcessGO:0043085positive regulation of catalytic activityIMPJ:158405
Biological ProcessGO:0051781positive regulation of cell divisionIEAJ:60000
Biological ProcessGO:2000467positive regulation of glycogen (starch) synthase activityIMPJ:158405
Biological ProcessGO:0045725positive regulation of glycogen biosynthetic processIMPJ:158405
Biological ProcessGO:0046628positive regulation of insulin receptor signaling pathwayISOJ:164563
Biological ProcessGO:0046628positive regulation of insulin receptor signaling pathwayIMPJ:158405
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:164563
Biological ProcessGO:0045840positive regulation of mitotic nuclear divisionISOJ:164563
Biological ProcessGO:0040018positive regulation of multicellular organism growthIMPJ:41236
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationIMPJ:158405
Biological ProcessGO:0051897positive regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationIMPJ:158405
Biological ProcessGO:0090031positive regulation of steroid hormone biosynthetic processISOJ:155856
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIGIJ:138783
Biological ProcessGO:0042493response to drugISOJ:155856
Biological ProcessGO:0035094response to nicotineISOJ:155856
Biological ProcessGO:0014070response to organic cyclic compoundISOJ:155856
Biological ProcessGO:0051146striated muscle cell differentiationIGIJ:138783

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.02
The Jackson Laboratory