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GO Annotations Graph
5-hydroxytryptamine (serotonin) receptor 1A

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0008144drug bindingISOJ:155856
Molecular FunctionGO:0001965G-protein alpha-subunit bindingISOJ:155856
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:72247
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:60000
Molecular FunctionGO:0051378serotonin bindingISOJ:155856
Molecular FunctionGO:0004993serotonin receptor activityISOJ:155856
Molecular FunctionGO:0004993serotonin receptor activityIDAJ:16036
Molecular FunctionGO:0004993serotonin receptor activityIMPJ:51280
Molecular FunctionGO:0004993serotonin receptor activityISOJ:164563
Molecular FunctionGO:0004871signal transducer activityIEAJ:60000
Cellular ComponentGO:0043203axon hillockISOJ:155856
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0016020membraneISOJ:155856
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0007198adenylate cyclase-inhibiting serotonin receptor signaling pathwayISOJ:155856
Biological ProcessGO:0007198adenylate cyclase-inhibiting serotonin receptor signaling pathwayISOJ:164563
Biological ProcessGO:0007610behaviorIEAJ:60000
Biological ProcessGO:0001662behavioral fear responseIMPJ:51280
Biological ProcessGO:0008283cell proliferationIEAJ:72247
Biological ProcessGO:0035640exploration behaviorIMPJ:51280
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayISOJ:164563
Biological ProcessGO:0097114NMDA glutamate receptor clusteringISOJ:155856
Biological ProcessGO:0031117positive regulation of microtubule depolymerizationISOJ:155856
Biological ProcessGO:0050795regulation of behaviorIEAJ:72247
Biological ProcessGO:0042053regulation of dopamine metabolic processIMPJ:65662
Biological ProcessGO:0060259regulation of feeding behaviorISOJ:155856
Biological ProcessGO:0046883regulation of hormone secretionIEAJ:72247
Biological ProcessGO:0014062regulation of serotonin secretionIMPJ:51280
Biological ProcessGO:0042428serotonin metabolic processIMPJ:65662
Biological ProcessGO:0007210serotonin receptor signaling pathwayISOJ:155856
Biological ProcessGO:0007210serotonin receptor signaling pathwayIMPJ:51280
Biological ProcessGO:0007165signal transductionIEAJ:60000
Biological ProcessGO:0042310vasoconstrictionIEAJ:72247

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.02
The Jackson Laboratory