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GO Annotations Graph
neuregulin 1

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Tue May 26 10:42:04 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005176ErbB-2 class receptor bindingIGIJ:42549
Molecular FunctionGO:0005176ErbB-2 class receptor bindingIDAJ:70080
Molecular FunctionGO:0030296protein tyrosine kinase activator activityIBAJ:161428
Molecular FunctionGO:0003712transcription cofactor activityISOJ:91050
Cellular ComponentGO:0030424axonIDAJ:90038
Cellular ComponentGO:0030424axonIDAJ:158973
Cellular ComponentGO:0005737cytoplasmIDAJ:50592
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:109116
Cellular ComponentGO:0005576extracellular regionIDAJ:109116
Cellular ComponentGO:0005615extracellular spaceIBAJ:161428
Cellular ComponentGO:0005887integral component of plasma membraneIDAJ:70080
Cellular ComponentGO:0031594neuromuscular junctionIDAJ:29667
Cellular ComponentGO:0005886plasma membraneIDAJ:50592
Cellular ComponentGO:0045202synapseIDAJ:22296
Biological ProcessGO:0007171activation of transmembrane receptor protein tyrosine kinase activityIBAJ:161428
Biological ProcessGO:0008366axon ensheathmentIMPJ:100989
Biological ProcessGO:0003161cardiac conduction system developmentIDAJ:78367
Biological ProcessGO:0016477cell migrationIGIJ:42549
Biological ProcessGO:0000902cell morphogenesisIDAJ:42549
Biological ProcessGO:0043624cellular protein complex disassemblyISOJ:73065
Biological ProcessGO:0010001glial cell differentiationIMPJ:82745
Biological ProcessGO:0010001glial cell differentiationIMPJ:109028
Biological ProcessGO:0021781glial cell fate commitmentIDAJ:166449
Biological ProcessGO:0007507heart developmentIMPJ:29971
Biological ProcessGO:0007507heart developmentIMPJ:33038
Biological ProcessGO:0007507heart developmentIMPJ:45302
Biological ProcessGO:0007626locomotory behaviorIMPJ:62377
Biological ProcessGO:0000165MAPK cascadeIDAJ:34173
Biological ProcessGO:0007517muscle organ developmentIMPJ:80793
Biological ProcessGO:0042177negative regulation of protein catabolic processIDAJ:160700
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedISOJ:91050
Biological ProcessGO:0007399nervous system developmentIMPJ:33038
Biological ProcessGO:0048663neuron fate commitmentIMPJ:70080
Biological ProcessGO:0045213neurotransmitter receptor metabolic processIMPJ:39800
Biological ProcessGO:0048709oligodendrocyte differentiationIMPJ:116863
Biological ProcessGO:0007422peripheral nervous system developmentIMPJ:29971
Biological ProcessGO:0007422peripheral nervous system developmentIMPJ:45302
Biological ProcessGO:0070886positive regulation of calcineurin-NFAT signaling cascadeIGIJ:144171
Biological ProcessGO:2000727positive regulation of cardiac muscle cell differentiationIMPJ:119151
Biological ProcessGO:0031643positive regulation of myelinationIMPJ:90038
Biological ProcessGO:0031643positive regulation of myelinationIMPJ:100989
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDAJ:109116
Biological ProcessGO:0045860positive regulation of protein kinase activityIDAJ:22296
Biological ProcessGO:0045860positive regulation of protein kinase activityIDAJ:58616
Biological ProcessGO:0051897positive regulation of protein kinase B signalingIDAJ:160700
Biological ProcessGO:0061098positive regulation of protein tyrosine kinase activityIBAJ:161428
Biological ProcessGO:0046579positive regulation of Ras protein signal transductionIDAJ:34173
Biological ProcessGO:0045595regulation of cell differentiationIMPJ:52282
Biological ProcessGO:0045595regulation of cell differentiationIMPJ:70080
Biological ProcessGO:0007416synapse assemblyIMPJ:60159

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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