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GO Annotations Graph
 Symbol
Name
ID
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
MGI:95820

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0051117ATPase bindingISOJ:155856
Molecular FunctionGO:0005262contributes_to
calcium channel activity
IGIJ:17924
Molecular FunctionGO:0005262calcium channel activityIMPJ:78374
Molecular FunctionGO:0005262calcium channel activityIMPJ:86846
Molecular FunctionGO:0005261cation channel activityIMPJ:34076
Molecular FunctionGO:0005261cation channel activityIMPJ:103735
Molecular FunctionGO:0005261contributes_to
cation channel activity
ISOJ:155856
Molecular FunctionGO:0050839cell adhesion molecule bindingISOJ:155856
Molecular FunctionGO:0005234contributes_to
extracellular-glutamate-gated ion channel activity
ISOJ:155856
Molecular FunctionGO:0005234extracellular-glutamate-gated ion channel activityIBAJ:161428
Molecular FunctionGO:0016595glutamate bindingISOJ:155856
Molecular FunctionGO:0035254glutamate receptor bindingISOJ:155856
Molecular FunctionGO:0005216ion channel activityIEAJ:72247
Molecular FunctionGO:0004970ionotropic glutamate receptor activityISOJ:155856
Molecular FunctionGO:0004970contributes_to
ionotropic glutamate receptor activity
ISOJ:155856
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIGIJ:1333
Molecular FunctionGO:0004972contributes_to
N-methyl-D-aspartate selective glutamate receptor activity
IGIJ:17924
Molecular FunctionGO:0004972contributes_to
N-methyl-D-aspartate selective glutamate receptor activity
IGIJ:20537
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:22295
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:34076
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:46495
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:78374
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:89820
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:103735
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:109557
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityIMPJ:110920
Molecular FunctionGO:0004972N-methyl-D-aspartate selective glutamate receptor activityISOJ:155856
Molecular FunctionGO:0042165neurotransmitter bindingISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:37859
Molecular FunctionGO:0005515protein bindingIPIJ:48437
Molecular FunctionGO:0005515protein bindingIPIJ:86846
Molecular FunctionGO:0005515protein bindingIPIJ:95556
Molecular FunctionGO:0005515protein bindingIPIJ:106962
Molecular FunctionGO:0005515protein bindingIPIJ:116426
Molecular FunctionGO:0005515protein bindingIPIJ:119798
Molecular FunctionGO:0005515protein bindingIPIJ:145582
Molecular FunctionGO:0005515protein bindingIPIJ:145953
Molecular FunctionGO:0005515protein bindingIPIJ:152628
Molecular FunctionGO:0032403protein complex bindingISOJ:155856
Molecular FunctionGO:0046983protein dimerization activityISOJ:155856
Molecular FunctionGO:0046982protein heterodimerization activityISOJ:155856
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0004872receptor activityIEAJ:72247
Molecular FunctionGO:0005102receptor bindingISOJ:155856
Molecular FunctionGO:0097110scaffold protein bindingISOJ:155856
Molecular FunctionGO:0005215transporter activityIEAJ:72247
Molecular FunctionGO:0022843voltage-gated cation channel activityISOJ:155856
Molecular FunctionGO:0008270zinc ion bindingISOJ:155856
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0009986cell surfaceIDAJ:128028
Cellular ComponentGO:0043197dendritic spineISAJ:101619
Cellular ComponentGO:0005783endoplasmic reticulumIDAJ:111556
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIDAJ:34361
Cellular ComponentGO:0016020membraneIDAJ:37859
Cellular ComponentGO:0016020membraneIDAJ:169741
Cellular ComponentGO:0017146N-methyl-D-aspartate selective glutamate receptor complexIPIJ:20537
Cellular ComponentGO:0017146N-methyl-D-aspartate selective glutamate receptor complexIPIJ:37859
Cellular ComponentGO:0017146N-methyl-D-aspartate selective glutamate receptor complexISOJ:155856
Cellular ComponentGO:0017146N-methyl-D-aspartate selective glutamate receptor complexISOJ:164563
Cellular ComponentGO:0043005neuron projectionISOJ:155856
Cellular ComponentGO:0043005neuron projectionIDAJ:173402
Cellular ComponentGO:0097481neuronal postsynaptic densityIDAJ:175650
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0014069postsynaptic densityIDAJ:92648
Cellular ComponentGO:0014069postsynaptic densityISOJ:155856
Cellular ComponentGO:0045211postsynaptic membraneIDAJ:80744
Cellular ComponentGO:0045211postsynaptic membraneIDAJ:84686
Cellular ComponentGO:0042734presynaptic membraneIDAJ:114728
Cellular ComponentGO:0042734presynaptic membraneISOJ:155856
Cellular ComponentGO:0045202synapseIDAJ:86623
Cellular ComponentGO:0045202synapseIDAJ:86846
Cellular ComponentGO:0045202synapseIDAJ:119025
Cellular ComponentGO:0008021synaptic vesicleIDAJ:160616
Cellular ComponentGO:0043195terminal boutonISOJ:155856
Biological ProcessGO:0001508action potentialISOJ:155856
Biological ProcessGO:0070588calcium ion transmembrane transportIMPJ:78374
Biological ProcessGO:0006816calcium ion transportIGIJ:17924
Biological ProcessGO:0006816calcium ion transportIMPJ:78374
Biological ProcessGO:0006816calcium ion transportIMPJ:86846
Biological ProcessGO:0006816calcium ion transportIMPJ:101085
Biological ProcessGO:0006812cation transportISOJ:155856
Biological ProcessGO:0071230cellular response to amino acid stimulusISOJ:155856
Biological ProcessGO:0071294cellular response to zinc ionISOJ:155856
Biological ProcessGO:0033058directional locomotionIGIJ:66455
Biological ProcessGO:0042417dopamine metabolic processIMPJ:78374
Biological ProcessGO:0034220ion transmembrane transportIGIJ:1333
Biological ProcessGO:0034220ion transmembrane transportISOJ:155856
Biological ProcessGO:0006811ion transportIEAJ:60000
Biological ProcessGO:0006811ion transportIEAJ:72247
Biological ProcessGO:0035235ionotropic glutamate receptor signaling pathwayIGIJ:1333
Biological ProcessGO:0035235ionotropic glutamate receptor signaling pathwayISOJ:155856
Biological ProcessGO:0007612learningIMPJ:78374
Biological ProcessGO:0007612learningIMPJ:103735
Biological ProcessGO:0007611learning or memoryIMPJ:49227
Biological ProcessGO:0007611learning or memoryIMPJ:101085
Biological ProcessGO:0040011locomotionIMPJ:78374
Biological ProcessGO:0040011locomotionIMPJ:89820
Biological ProcessGO:0007626locomotory behaviorTASJ:113959
Biological ProcessGO:0007613memoryIMPJ:45446
Biological ProcessGO:0007613memoryISOJ:155856
Biological ProcessGO:0042177negative regulation of protein catabolic processIGIJ:92648
Biological ProcessGO:0022008neurogenesisIMPJ:102617
Biological ProcessGO:0043065positive regulation of apoptotic processIGIJ:125170
Biological ProcessGO:0010942positive regulation of cell deathISOJ:155856
Biological ProcessGO:2000463positive regulation of excitatory postsynaptic membrane potentialISOJ:155856
Biological ProcessGO:0008104protein localizationIGIJ:92648
Biological ProcessGO:0008104protein localizationIMPJ:92648
Biological ProcessGO:0051262protein tetramerizationISOJ:155856
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIMPJ:34076
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIMPJ:41902
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIMPJ:66455
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIGIJ:66455
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIMPJ:85901
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIMPJ:86846
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIMPJ:101085
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialIMPJ:114728
Biological ProcessGO:0060079regulation of excitatory postsynaptic membrane potentialISOJ:155856
Biological ProcessGO:0034765regulation of ion transmembrane transportISOJ:155856
Biological ProcessGO:0048169regulation of long-term neuronal synaptic plasticityISOJ:155856
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:22295
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:49227
Biological ProcessGO:0060078regulation of postsynaptic membrane potentialIMPJ:114728
Biological ProcessGO:0051930regulation of sensory perception of painIMPJ:119596
Biological ProcessGO:0048167regulation of synaptic plasticityIMPJ:113959
Biological ProcessGO:0050804regulation of synaptic transmissionIMPJ:113959
Biological ProcessGO:0001975response to amphetamineIMPJ:112494
Biological ProcessGO:0042493response to drugIMPJ:89820
Biological ProcessGO:0045471response to ethanolIMPJ:85901
Biological ProcessGO:0045471response to ethanolISOJ:164563
Biological ProcessGO:0009611response to woundingIGIJ:46495
Biological ProcessGO:0009611response to woundingIMPJ:51277
Biological ProcessGO:0048511rhythmic processISOJ:155856
Biological ProcessGO:0019233sensory perception of painIMPJ:60443
Biological ProcessGO:0042428serotonin metabolic processIMPJ:78374
Biological ProcessGO:0030431sleepIMPJ:109557
Biological ProcessGO:0001964startle responseIMPJ:89405
Biological ProcessGO:0001964startle responseIGIJ:101790
Biological ProcessGO:0007268synaptic transmissionIMPJ:41902
Biological ProcessGO:0007268synaptic transmissionISOJ:155856
Biological ProcessGO:0035249synaptic transmission, glutamatergicIBAJ:161428
Biological ProcessGO:0006810transportIEAJ:60000
Biological ProcessGO:0006810transportIEAJ:72247
Biological ProcessGO:0008542visual learningIMPJ:22295

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory