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GO Annotations Graph
 Symbol
Name
ID
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
MGI:88105

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0043531ADP bindingISOJ:155856
Molecular FunctionGO:0030506ankyrin bindingISOJ:155856
Molecular FunctionGO:0005524ATP bindingISOJ:155856
Molecular FunctionGO:0019829cation-transporting ATPase activityIEAJ:72247
Molecular FunctionGO:0051087chaperone bindingISOJ:155856
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0016820hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:72247
Molecular FunctionGO:0015077monovalent inorganic cation transmembrane transporter activityIEAJ:72247
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:72247
Molecular FunctionGO:0016791phosphatase activityIMPJ:55191
Molecular FunctionGO:0043548phosphatidylinositol 3-kinase bindingISOJ:155856
Molecular FunctionGO:0030955potassium ion bindingISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:95157
Molecular FunctionGO:0005515protein bindingIPIJ:103813
Molecular FunctionGO:0019904protein domain specific bindingISOJ:155856
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0031402sodium ion bindingISOJ:155856
Molecular FunctionGO:0005391sodium:potassium-exchanging ATPase activityIMPJ:55191
Molecular FunctionGO:0005391sodium:potassium-exchanging ATPase activityIMPJ:95157
Molecular FunctionGO:0005391sodium:potassium-exchanging ATPase activityISOJ:155856
Molecular FunctionGO:0005391sodium:potassium-exchanging ATPase activityIDAJ:203477
Cellular ComponentGO:0016324apical plasma membraneIDAJ:176751
Cellular ComponentGO:0016323basolateral plasma membraneIDAJ:18532
Cellular ComponentGO:0005901caveolaISOJ:155856
Cellular ComponentGO:0005783endoplasmic reticulumISOJ:155856
Cellular ComponentGO:0005768endosomeISOJ:155856
Cellular ComponentGO:0070062extracellular vesicular exosomeISOJ:164563
Cellular ComponentGO:0005794Golgi apparatusISOJ:155856
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0016020membraneISOJ:155856
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0005886plasma membraneIDAJ:62912
Cellular ComponentGO:0005886plasma membraneIDAJ:119891
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0043234protein complexISOJ:199676
Cellular ComponentGO:0042383sarcolemmaIDAJ:95157
Cellular ComponentGO:0042383sarcolemmaIDAJ:103813
Cellular ComponentGO:0005890sodium:potassium-exchanging ATPase complexISOJ:155856
Cellular ComponentGO:0030315T-tubuleIDAJ:103813
Biological ProcessGO:0006754ATP biosynthetic processIEAJ:72247
Biological ProcessGO:0006200ATP catabolic processIMPJ:55191
Biological ProcessGO:0006812cation transportIEAJ:72247
Biological ProcessGO:0071260cellular response to mechanical stimulusISOJ:155856
Biological ProcessGO:0016311dephosphorylationIMPJ:55191
Biological ProcessGO:0006811ion transportIEAJ:60000
Biological ProcessGO:0060081membrane hyperpolarizationISOJ:155856
Biological ProcessGO:0015672monovalent inorganic cation transportIEAJ:72247
Biological ProcessGO:0031947negative regulation of glucocorticoid biosynthetic processIMPJ:117414
Biological ProcessGO:0045822negative regulation of heart contractionIMPJ:95157
Biological ProcessGO:0045823positive regulation of heart contractionIMPJ:55191
Biological ProcessGO:0045989positive regulation of striated muscle contractionIMPJ:114415
Biological ProcessGO:0010107potassium ion importISOJ:155856
Biological ProcessGO:0071805potassium ion transmembrane transportIMPJ:55191
Biological ProcessGO:0006813potassium ion transportISOJ:155856
Biological ProcessGO:0008217regulation of blood pressureIGIJ:102928
Biological ProcessGO:0086004regulation of cardiac muscle cell contractionISOJ:155856
Biological ProcessGO:0002028regulation of sodium ion transportISOJ:155856
Biological ProcessGO:0002026regulation of the force of heart contractionIMPJ:55191
Biological ProcessGO:0002026regulation of the force of heart contractionIMPJ:95157
Biological ProcessGO:0042493response to drugIMPJ:117414
Biological ProcessGO:0035725sodium ion transmembrane transportIMPJ:55191
Biological ProcessGO:0035725sodium ion transmembrane transportISOJ:155856
Biological ProcessGO:0006814sodium ion transportISOJ:155856
Biological ProcessGO:0006810transportIEAJ:60000

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory