About   Help   FAQ
GO Annotations Graph
ATP-binding cassette, sub-family A (ABC1), member 12

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0034191apolipoprotein A-I receptor bindingISOJ:164563
Molecular FunctionGO:0042626ATPase activity, coupled to transmembrane movement of substancesIBAJ:161428
Molecular FunctionGO:0017127cholesterol transporter activityIBAJ:161428
Molecular FunctionGO:0005319lipid transporter activityISOJ:164563
Molecular FunctionGO:0005548phospholipid transporter activityIBAJ:161428
Molecular FunctionGO:0005515protein bindingIPIJ:200990
Molecular FunctionGO:0005515protein bindingIPIJ:200990
Molecular FunctionGO:0005102receptor bindingISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005829cytosolIDAJ:139048
Cellular ComponentGO:0097209epidermal lamellar bodyISOJ:164563
Cellular ComponentGO:0005887integral component of plasma membraneIBAJ:161428
Cellular ComponentGO:0043231intracellular membrane-bounded organelleIBAJ:161428
Cellular ComponentGO:0005743mitochondrial inner membraneIDAJ:100953
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0035627ceramide transportIMPJ:144062
Biological ProcessGO:0033344cholesterol effluxIBAJ:161428
Biological ProcessGO:0061436establishment of skin barrierIMPJ:139048
Biological ProcessGO:0061436establishment of skin barrierIMPJ:144062
Biological ProcessGO:0061436establishment of skin barrierIMPJ:161652
Biological ProcessGO:0031424keratinizationIMPJ:139048
Biological ProcessGO:0031424keratinizationIMPJ:144062
Biological ProcessGO:0031424keratinizationIMPJ:161652
Biological ProcessGO:0030216keratinocyte differentiationIMPJ:161652
Biological ProcessGO:0055088lipid homeostasisIMPJ:161652
Biological ProcessGO:0006869lipid transportISOJ:164563
Biological ProcessGO:0048286lung alveolus developmentIMPJ:139048
Biological ProcessGO:0033700phospholipid effluxISOJ:164563
Biological ProcessGO:0033700phospholipid effluxIBAJ:161428
Biological ProcessGO:0010875positive regulation of cholesterol effluxISOJ:164563
Biological ProcessGO:0010875positive regulation of cholesterol effluxIGIJ:200990
Biological ProcessGO:0010875positive regulation of cholesterol effluxIMPJ:200990
Biological ProcessGO:2000010positive regulation of protein localization to cell surfaceIMPJ:200990
Biological ProcessGO:0072659protein localization to plasma membraneISOJ:164563
Biological ProcessGO:0045055regulated secretory pathwayISOJ:164563
Biological ProcessGO:0032940secretion by cellISOJ:164563
Biological ProcessGO:0043129surfactant homeostasisIMPJ:139048
Biological ProcessGO:0055085transmembrane transportIBAJ:161428

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.02
The Jackson Laboratory