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GO Annotations Graph
 Symbol
Name
ID
Tph2
tryptophan hydroxylase 2
MGI:2651811

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0016597amino acid bindingIEAJ:72247
Molecular FunctionGO:0005506iron ion bindingIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0004497monooxygenase activityIEAJ:60000
Molecular FunctionGO:0004497monooxygenase activityIEAJ:72247
Molecular FunctionGO:0016491oxidoreductase activityIEAJ:60000
Molecular FunctionGO:0016714oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygenIEAJ:72247
Molecular FunctionGO:0004510tryptophan 5-monooxygenase activityIDAJ:81435
Cellular ComponentGO:0043005neuron projectionIDAJ:154739
Biological ProcessGO:0009072aromatic amino acid family metabolic processIEAJ:72247
Biological ProcessGO:0008152metabolic processIEAJ:72247
Biological ProcessGO:0055114oxidation-reduction processIDAJ:81435
Biological ProcessGO:0042427serotonin biosynthetic processIEAJ:60000
Biological ProcessGO:0042427serotonin biosynthetic processIEAJ:72247
Biological ProcessGO:0006587serotonin biosynthetic process from tryptophanICJ:82435

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory