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GO Annotations Graph
interleukin 23, alpha subunit p19

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005125cytokine activityIEAJ:60000
Molecular FunctionGO:0005125cytokine activityIEAJ:72247
Molecular FunctionGO:0045519contributes_to
interleukin-23 receptor binding
Molecular FunctionGO:0045519contributes_to
interleukin-23 receptor binding
Molecular FunctionGO:0005515protein bindingIPIJ:65966
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005576extracellular regionIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceIDAJ:168000
Cellular ComponentGO:0070743interleukin-23 complexISOJ:164563
Biological ProcessGO:0050829defense response to Gram-negative bacteriumISOJ:164563
Biological ProcessGO:0051607defense response to virusIEAJ:60000
Biological ProcessGO:0006955immune responseIEAJ:72247
Biological ProcessGO:0002376immune system processIEAJ:60000
Biological ProcessGO:0006954inflammatory responseIEAJ:60000
Biological ProcessGO:0045087innate immune responseIEAJ:60000
Biological ProcessGO:0032693negative regulation of interleukin-10 productionISOJ:164563
Biological ProcessGO:0042104positive regulation of activated T cell proliferationISOJ:164563
Biological ProcessGO:0010535positive regulation of activation of JAK2 kinase activityISOJ:164563
Biological ProcessGO:0002230positive regulation of defense response to virus by hostIDAJ:87643
Biological ProcessGO:0002230positive regulation of defense response to virus by hostISOJ:164563
Biological ProcessGO:0032725positive regulation of granulocyte macrophage colony-stimulating factor productionISOJ:164563
Biological ProcessGO:0032729positive regulation of interferon-gamma productionISOJ:164563
Biological ProcessGO:0032733positive regulation of interleukin-10 productionISOJ:164563
Biological ProcessGO:0032735positive regulation of interleukin-12 productionISOJ:164563
Biological ProcessGO:0032740positive regulation of interleukin-17 productionISOJ:164563
Biological ProcessGO:0043382positive regulation of memory T cell differentiationIDAJ:87643
Biological ProcessGO:0032819positive regulation of natural killer cell proliferationISOJ:164563
Biological ProcessGO:0090023positive regulation of neutrophil chemotaxisIDAJ:147573
Biological ProcessGO:0051135positive regulation of NK T cell activationISOJ:164563
Biological ProcessGO:0051142positive regulation of NK T cell proliferationISOJ:164563
Biological ProcessGO:0045672positive regulation of osteoclast differentiationISOJ:164563
Biological ProcessGO:0001916positive regulation of T cell mediated cytotoxicityIDAJ:87643
Biological ProcessGO:0042102positive regulation of T cell proliferationISOJ:164563
Biological ProcessGO:0002827positive regulation of T-helper 1 type immune responseIDAJ:87643
Biological ProcessGO:0002827positive regulation of T-helper 1 type immune responseISOJ:164563
Biological ProcessGO:2000330positive regulation of T-helper 17 cell lineage commitmentIDAJ:150655
Biological ProcessGO:2000318positive regulation of T-helper 17 type immune responseIDAJ:150655
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIGIJ:151963
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionISOJ:164563
Biological ProcessGO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinISOJ:164563
Biological ProcessGO:0042520positive regulation of tyrosine phosphorylation of Stat4 proteinISOJ:164563
Biological ProcessGO:0042523positive regulation of tyrosine phosphorylation of Stat5 proteinISOJ:164563
Biological ProcessGO:0042510regulation of tyrosine phosphorylation of Stat1 proteinISOJ:164563
Biological ProcessGO:0042098T cell proliferationIDAJ:124638
Biological ProcessGO:0048771tissue remodelingIEAJ:60000

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory