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GO Annotations Graph
 Symbol
Name
ID
Sirt3
sirtuin 3
MGI:1927665

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Fri Jan 17 13:56:29 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0031078histone deacetylase activity (H3-K14 specific)IEAJ:72245
Molecular FunctionGO:0032129histone deacetylase activity (H3-K9 specific)IEAJ:72245
Molecular FunctionGO:0034739histone deacetylase activity (H4-K16 specific)IEAJ:72245
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0016811hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidesIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0051287NAD bindingIEAJ:72247
Molecular FunctionGO:0070403NAD+ bindingIEAJ:72247
Molecular FunctionGO:0032041NAD-dependent histone deacetylase activity (H3-K14 specific)IDAJ:163964
Molecular FunctionGO:0097372NAD-dependent histone deacetylase activity (H3-K18 specific)IEAJ:72245
Molecular FunctionGO:0046969NAD-dependent histone deacetylase activity (H3-K9 specific)IEAJ:72245
Molecular FunctionGO:0046970NAD-dependent histone deacetylase activity (H4-K16 specific)IEAJ:72245
Molecular FunctionGO:0005515protein bindingIPIJ:174774
Molecular FunctionGO:0008270zinc ion bindingISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:65632
Cellular ComponentGO:0016020membraneIDAJ:65632
Cellular ComponentGO:0005739mitochondrionIDAJ:151002
Cellular ComponentGO:0005739mitochondrionIDAJ:163964
Cellular ComponentGO:0005739mitochondrionISOJ:164563
Biological ProcessGO:0009060aerobic respirationISOJ:164563
Biological ProcessGO:0070932histone H3 deacetylationIDAJ:163964
Biological ProcessGO:0034983peptidyl-lysine deacetylationISOJ:164563
Biological ProcessGO:0006476protein deacetylationIDAJ:163964
Biological ProcessGO:0006476protein deacetylationISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory