About   Help   FAQ
GO Annotations Graph
interleukin 21

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005125cytokine activityIEAJ:60000
Molecular FunctionGO:0005126cytokine receptor bindingIDAJ:65629
Molecular FunctionGO:0005134interleukin-2 receptor bindingISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005615extracellular spaceIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceIEAJ:60000
Cellular ComponentGO:0005622intracellularISOJ:164563
Biological ProcessGO:0001783B cell apoptotic processNASJ:93740
Biological ProcessGO:0048469cell maturationISOJ:164563
Biological ProcessGO:0006955immune responseIEAJ:72247
Biological ProcessGO:0045579positive regulation of B cell differentiationNASJ:93740
Biological ProcessGO:0030890positive regulation of B cell proliferationISOJ:73065
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:73065
Biological ProcessGO:0001819positive regulation of cytokine productionISOJ:164563
Biological ProcessGO:0045078positive regulation of interferon-gamma biosynthetic processIDAJ:88003
Biological ProcessGO:0032733positive regulation of interleukin-10 productionIDAJ:88003
Biological ProcessGO:0032740positive regulation of interleukin-17 productionISOJ:164563
Biological ProcessGO:0002729positive regulation of natural killer cell cytokine productionIDAJ:88003
Biological ProcessGO:0032825positive regulation of natural killer cell differentiationIDAJ:88003
Biological ProcessGO:0045954positive regulation of natural killer cell mediated cytotoxicityISOJ:164563
Biological ProcessGO:0045954positive regulation of natural killer cell mediated cytotoxicityIDAJ:88003
Biological ProcessGO:0042102positive regulation of T cell proliferationISOJ:73065
Biological ProcessGO:0042511positive regulation of tyrosine phosphorylation of Stat1 proteinISOJ:73065
Biological ProcessGO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinISOJ:73065
Biological ProcessGO:0042503tyrosine phosphorylation of Stat3 proteinISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.02
The Jackson Laboratory