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GO Annotations Graph
platelet-derived growth factor, C polypeptide

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0008083growth factor activityIEAJ:60000
Molecular FunctionGO:0008083growth factor activityIEAJ:72247
Molecular FunctionGO:0005161platelet-derived growth factor receptor bindingISOJ:164563
Molecular FunctionGO:0005161platelet-derived growth factor receptor bindingIDAJ:62052
Molecular FunctionGO:0005161platelet-derived growth factor receptor bindingIDAJ:93392
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionIDAJ:62052
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0007171activation of transmembrane receptor protein tyrosine kinase activityIDAJ:62052
Biological ProcessGO:0060348bone developmentIGIJ:205009
Biological ProcessGO:0071230cellular response to amino acid stimulusIDAJ:164409
Biological ProcessGO:0048565digestive tract developmentIGIJ:205009
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:60000
Biological ProcessGO:0009887organ morphogenesisIGIJ:93954
Biological ProcessGO:0009887organ morphogenesisIMPJ:93954
Biological ProcessGO:0048008platelet-derived growth factor receptor signaling pathwayIDAJ:93392
Biological ProcessGO:0048008platelet-derived growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0051781positive regulation of cell divisionIEAJ:60000
Biological ProcessGO:0008284positive regulation of cell proliferationIDAJ:62052
Biological ProcessGO:0008284positive regulation of cell proliferationIDAJ:93354
Biological ProcessGO:0045740positive regulation of DNA replicationISOJ:164563
Biological ProcessGO:0048146positive regulation of fibroblast proliferationISOJ:164563
Biological ProcessGO:0050730regulation of peptidyl-tyrosine phosphorylationIDAJ:77668

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.02
The Jackson Laboratory