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GO Annotations Graph
large tumor suppressor 2

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0005815microtubule organizing centerISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:73065
Cellular ComponentGO:0000922spindle poleIDAJ:93191
Cellular ComponentGO:0000922spindle poleISOJ:164563
Biological ProcessGO:0007049cell cycleIEAJ:60000
Biological ProcessGO:0051301cell divisionIEAJ:60000
Biological ProcessGO:0034613cellular protein localizationIGIJ:147050
Biological ProcessGO:0034613cellular protein localizationIDAJ:147050
Biological ProcessGO:0000082G1/S transition of mitotic cell cycleIDAJ:93191
Biological ProcessGO:0000082G1/S transition of mitotic cell cycleISOJ:164563
Biological ProcessGO:0035329hippo signalingISOJ:164563
Biological ProcessGO:0035329hippo signalingIGIJ:134270
Biological ProcessGO:0009755hormone-mediated signaling pathwayISOJ:164563
Biological ProcessGO:0001827inner cell mass cell fate commitmentIGIJ:199456
Biological ProcessGO:0001828inner cell mass cellular morphogenesisIGIJ:199456
Biological ProcessGO:0035556intracellular signal transductionISOJ:164563
Biological ProcessGO:0030216keratinocyte differentiationIGIJ:134270
Biological ProcessGO:0007067mitotic nuclear divisionIEAJ:72247
Biological ProcessGO:0007067mitotic nuclear divisionIEAJ:60000
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayIGIJ:170963
Biological ProcessGO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activityISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0006468protein phosphorylationIDAJ:147050
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0046620regulation of organ growthIMPJ:170963

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.02
The Jackson Laboratory