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GO Annotations Graph
sprouty homolog 2 (Drosophila)

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005515protein bindingIPIJ:73116
Molecular FunctionGO:0005515protein bindingIPIJ:105250
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0043539protein serine/threonine kinase activator activityISOJ:164563
Cellular ComponentGO:0042995cell projectionIEAJ:60000
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0005874microtubuleIEAJ:60000
Cellular ComponentGO:0015630microtubule cytoskeletonISOJ:164563
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0048754branching morphogenesis of an epithelial tubeIMPJ:53234
Biological ProcessGO:0060449bud elongation involved in lung branchingIGIJ:174194
Biological ProcessGO:0045165cell fate commitmentIMPJ:98303
Biological ProcessGO:0045165cell fate commitmentIGIJ:98303
Biological ProcessGO:0000132establishment of mitotic spindle orientationIGIJ:174194
Biological ProcessGO:0042472inner ear morphogenesisIGIJ:98303
Biological ProcessGO:0042472inner ear morphogenesisIMPJ:98303
Biological ProcessGO:0030324lung developmentIMPJ:53234
Biological ProcessGO:0060437lung growthIDAJ:69279
Biological ProcessGO:0060425lung morphogenesisIDAJ:69279
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:72247
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:60000
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processIMPJ:131584
Biological ProcessGO:0008285negative regulation of cell proliferationIDAJ:73116
Biological ProcessGO:0070373negative regulation of ERK1 and ERK2 cascadeIDAJ:73116
Biological ProcessGO:0070373negative regulation of ERK1 and ERK2 cascadeIGIJ:174194
Biological ProcessGO:0040037negative regulation of fibroblast growth factor receptor signaling pathwayIDAJ:73116
Biological ProcessGO:0040037negative regulation of fibroblast growth factor receptor signaling pathwayIGIJ:98303
Biological ProcessGO:0034260negative regulation of GTPase activityIDAJ:73116
Biological ProcessGO:0043407negative regulation of MAP kinase activityIDAJ:105250
Biological ProcessGO:0051387negative regulation of neurotrophin TRK receptor signaling pathwayIDAJ:73116
Biological ProcessGO:0010801negative regulation of peptidyl-threonine phosphorylationISOJ:164563
Biological ProcessGO:0046580negative regulation of Ras protein signal transductionIDAJ:73116
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:164563
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:0051897positive regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0071902positive regulation of protein serine/threonine kinase activityISOJ:164563
Biological ProcessGO:0045595regulation of cell differentiationIEAJ:72247
Biological ProcessGO:0042127regulation of cell proliferationIEAJ:72247
Biological ProcessGO:0009966regulation of signal transductionIEAJ:72247
Biological ProcessGO:0060541respiratory system developmentIDAJ:69279
Biological ProcessGO:0007605sensory perception of soundIMPJ:98303

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.02
The Jackson Laboratory