About   Help   FAQ
GO Annotations Graph
 Symbol
Name
ID
Pdpk1
3-phosphoinositide dependent protein kinase 1
MGI:1338068

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:00046763-phosphoinositide-dependent protein kinase activityIDAJ:53564
Molecular FunctionGO:00046763-phosphoinositide-dependent protein kinase activityISOJ:155856
Molecular FunctionGO:00046763-phosphoinositide-dependent protein kinase activityISOJ:164563
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005158insulin receptor bindingISOJ:155856
Molecular FunctionGO:0016301kinase activityISOJ:164563
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0016004phospholipase activator activityISOJ:164563
Molecular FunctionGO:0043274phospholipase bindingISOJ:164563
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0016772transferase activity, transferring phosphorus-containing groupsIEAJ:72247
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0042995cell projectionISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:85182
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0016023cytoplasmic membrane-bounded vesicleIDAJ:85182
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0032148activation of protein kinase B activityISOJ:164563
Biological ProcessGO:0019722calcium-mediated signalingISOJ:164563
Biological ProcessGO:0016477cell migrationISOJ:164563
Biological ProcessGO:0071364cellular response to epidermal growth factor stimulusISOJ:164563
Biological ProcessGO:0032869cellular response to insulin stimulusISOJ:164563
Biological ProcessGO:0007173epidermal growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0097191extrinsic apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0048041focal adhesion assemblyISOJ:155856
Biological ProcessGO:0006972hyperosmotic responseIDAJ:85182
Biological ProcessGO:0010667negative regulation of cardiac muscle cell apoptotic processIMPJ:150014
Biological ProcessGO:0006469negative regulation of protein kinase activityISOJ:164563
Biological ProcessGO:0034122negative regulation of toll-like receptor signaling pathwayIMPJ:163291
Biological ProcessGO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayISOJ:164563
Biological ProcessGO:0018107peptidyl-threonine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0090004positive regulation of establishment of protein localization to plasma membraneISOJ:164563
Biological ProcessGO:0010518positive regulation of phospholipase activityISOJ:164563
Biological ProcessGO:0051281positive regulation of release of sequestered calcium ion into cytosolISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIDAJ:53564
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0010594regulation of endothelial cell migrationIMPJ:134712
Biological ProcessGO:0043122regulation of I-kappaB kinase/NF-kappaB signalingISOJ:164563
Biological ProcessGO:0043304regulation of mast cell degranulationIMPJ:178435
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0007165signal transductionTASJ:53564
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0003323type B pancreatic cell developmentIMPJ:153548

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory