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GO Annotations Graph
caspase 12

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0004197cysteine-type endopeptidase activityIBAJ:161428
Molecular FunctionGO:0008234cysteine-type peptidase activityISOJ:155856
Molecular FunctionGO:0004175endopeptidase activityISOJ:155856
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0008233peptidase activityRCAJ:84168
Molecular FunctionGO:0002020protease bindingISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:87334
Molecular FunctionGO:0005515protein bindingIPIJ:186075
Cellular ComponentGO:0005737cytoplasmIBAJ:161428
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005783endoplasmic reticulumTASJ:87334
Cellular ComponentGO:0005622intracellularIGIJ:84272
Cellular ComponentGO:0043231intracellular membrane-bounded organelleISOJ:155856
Cellular ComponentGO:0005634nucleusISOJ:155856
Biological ProcessGO:0006915apoptotic processIDAJ:84272
Biological ProcessGO:0030968endoplasmic reticulum unfolded protein responseIDAJ:62257
Biological ProcessGO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressIGIJ:84272
Biological ProcessGO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressTASJ:180458
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:155856
Biological ProcessGO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic processISOJ:155856
Biological ProcessGO:0016540protein autoprocessingISOJ:155856
Biological ProcessGO:0006508proteolysisRCAJ:84168
Biological ProcessGO:0006508proteolysisISOJ:155856
Biological ProcessGO:0006508proteolysisIBAJ:161428
Biological ProcessGO:0042981regulation of apoptotic processIEAJ:72247

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory