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GO Annotations Graph
 Symbol
Name
ID
Cxcr3
chemokine (C-X-C motif) receptor 3
MGI:1277207

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0019958C-X-C chemokine bindingISOJ:164563
Molecular FunctionGO:0016494C-X-C chemokine receptor activityISOJ:155856
Molecular FunctionGO:0019956chemokine bindingISOJ:164563
Molecular FunctionGO:0004950chemokine receptor activityISOJ:155856
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:60000
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:72247
Molecular FunctionGO:0004872receptor activityISOJ:164563
Molecular FunctionGO:0004871signal transducer activityIEAJ:60000
Cellular ComponentGO:0009986cell surfaceIDAJ:200103
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:141392
Cellular ComponentGO:0009897external side of plasma membraneISOJ:155856
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005622intracellularISOJ:155856
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0001525angiogenesisIEAJ:60000
Biological ProcessGO:0019722calcium-mediated signalingISOJ:155856
Biological ProcessGO:0007166cell surface receptor signaling pathwayISOJ:164563
Biological ProcessGO:0071954chemokine (C-C motif) ligand 11 productionISOJ:164563
Biological ProcessGO:0070098chemokine-mediated signaling pathwayISOJ:155856
Biological ProcessGO:0006935chemotaxisIEAJ:60000
Biological ProcessGO:0006935chemotaxisIEAJ:72247
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayISOJ:164563
Biological ProcessGO:0006954inflammatory responseIEAJ:72247
Biological ProcessGO:0016525negative regulation of angiogenesisISOJ:164563
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:1900118negative regulation of execution phase of apoptosisISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:164563
Biological ProcessGO:0030816positive regulation of cAMP metabolic processISOJ:164563
Biological ProcessGO:0043950positive regulation of cAMP-mediated signalingISOJ:164563
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:164563
Biological ProcessGO:0050921positive regulation of chemotaxisISOJ:164563
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationISOJ:155856
Biological ProcessGO:1900119positive regulation of execution phase of apoptosisISOJ:164563
Biological ProcessGO:0051281positive regulation of release of sequestered calcium ion into cytosolISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0002685regulation of leukocyte migrationIEAJ:72247
Biological ProcessGO:0007165signal transductionIEAJ:60000
Biological ProcessGO:0010818T cell chemotaxisISOJ:155856

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory