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GO Annotations Graph
telomerase reverse transcriptase

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003677DNA bindingIEAJ:60000
Molecular FunctionGO:0003677DNA bindingIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0016779nucleotidyltransferase activityIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:72504
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0003964RNA-directed DNA polymerase activityIEAJ:60000
Molecular FunctionGO:0003964RNA-directed DNA polymerase activityIEAJ:72245
Molecular FunctionGO:0003964RNA-directed DNA polymerase activityIEAJ:72247
Molecular FunctionGO:0003720telomerase activityIDAJ:87581
Molecular FunctionGO:0003720telomerase activityISOJ:164563
Molecular FunctionGO:0070034telomeric RNA bindingISOJ:164563
Molecular FunctionGO:0003721telomeric template RNA reverse transcriptase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005694chromosomeIEAJ:60000
Cellular ComponentGO:0000781chromosome, telomeric regionIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0016605colocalizes_with
PML body
Cellular ComponentGO:0030529ribonucleoprotein complexIEAJ:60000
Cellular ComponentGO:0005697telomerase holoenzyme complexISOJ:164563
Biological ProcessGO:0071897DNA biosynthetic processISOJ:164563
Biological ProcessGO:0022616DNA strand elongationISOJ:164563
Biological ProcessGO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligandISOJ:164563
Biological ProcessGO:0090399replicative senescenceISOJ:164563
Biological ProcessGO:0006278RNA-dependent DNA replicationIDAJ:87581
Biological ProcessGO:0032203telomere formation via telomeraseISOJ:164563
Biological ProcessGO:0007004telomere maintenance via telomeraseISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
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