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GO Annotations Graph
 Symbol
Name
ID
Fzd1
frizzled homolog 1 (Drosophila)
MGI:1196625

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005109frizzled bindingISOJ:164563
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:60000
Molecular FunctionGO:0042802identical protein bindingISOJ:155856
Molecular FunctionGO:0030165PDZ domain bindingIBAJ:161428
Molecular FunctionGO:0030165PDZ domain bindingISOJ:164563
Molecular FunctionGO:0046982protein heterodimerization activityISOJ:155856
Molecular FunctionGO:0042803protein homodimerization activityISOJ:155856
Molecular FunctionGO:0005102receptor bindingISOJ:164563
Molecular FunctionGO:0004871signal transducer activityIEAJ:60000
Molecular FunctionGO:0004888transmembrane signaling receptor activityIEAJ:72247
Molecular FunctionGO:0042813Wnt-activated receptor activityIBAJ:161428
Molecular FunctionGO:0042813Wnt-activated receptor activityISOJ:164563
Molecular FunctionGO:0017147Wnt-protein bindingIPIJ:99178
Molecular FunctionGO:0017147Wnt-protein bindingISOJ:164563
Cellular ComponentGO:0045177apical part of cellIBAJ:161428
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmIBAJ:161428
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0043005neuron projectionISOJ:155856
Cellular ComponentGO:0032589neuron projection membraneIBAJ:161428
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Biological ProcessGO:0035425autocrine signalingISOJ:164563
Biological ProcessGO:0007409axonogenesisIBAJ:161428
Biological ProcessGO:0007420brain developmentIBAJ:161428
Biological ProcessGO:0060070canonical Wnt signaling pathwayIMPJ:91019
Biological ProcessGO:0060070canonical Wnt signaling pathwayISOJ:155856
Biological ProcessGO:0060070canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0044338canonical Wnt signaling pathway involved in mesenchymal stem cell differentiationISOJ:164563
Biological ProcessGO:0044339canonical Wnt signaling pathway involved in osteoblast differentiationISOJ:164563
Biological ProcessGO:0007166cell surface receptor signaling pathwayIEAJ:72247
Biological ProcessGO:0007267cell-cell signalingIDAJ:98305
Biological ProcessGO:0007267cell-cell signalingISOJ:164563
Biological ProcessGO:0030855epithelial cell differentiationIDAJ:98305
Biological ProcessGO:0030855epithelial cell differentiationIGIJ:98305
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayIEAJ:60000
Biological ProcessGO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAJ:161428
Biological ProcessGO:0008406gonad developmentIBAJ:161428
Biological ProcessGO:0060022hard palate developmentIGIJ:165556
Biological ProcessGO:0048286lung alveolus developmentIBAJ:161428
Biological ProcessGO:0003149membranous septum morphogenesisIGIJ:165556
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:60000
Biological ProcessGO:0003150muscular septum morphogenesisIGIJ:165556
Biological ProcessGO:0030514negative regulation of BMP signaling pathwayIDAJ:88480
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwayIDAJ:88490
Biological ProcessGO:0035414negative regulation of catenin import into nucleusIDAJ:88480
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedIMPJ:112463
Biological ProcessGO:0003151outflow tract morphogenesisIGIJ:165556
Biological ProcessGO:0090179planar cell polarity pathway involved in neural tube closureIGIJ:165556
Biological ProcessGO:0001934positive regulation of protein phosphorylationIMPJ:91019
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISOJ:155856
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0006357regulation of transcription from RNA polymerase II promoterIBAJ:161428
Biological ProcessGO:0042493response to drugISOJ:164563
Biological ProcessGO:0007165signal transductionIEAJ:60000
Biological ProcessGO:0001944vasculature developmentIBAJ:161428
Biological ProcessGO:0060412ventricular septum morphogenesisIGIJ:165556
Biological ProcessGO:0016055Wnt signaling pathwayIGIJ:99178
Biological ProcessGO:0016055Wnt signaling pathwayISOJ:155856
Biological ProcessGO:0007223Wnt signaling pathway, calcium modulating pathwayIBAJ:161428

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory