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GO Annotations Graph
MAP kinase-activated protein kinase 2

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:126340
Molecular FunctionGO:0005515protein bindingIPIJ:148784
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:126340
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:180488
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:180499
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0016772transferase activity, transferring phosphorus-containing groupsIEAJ:72247
Cellular ComponentGO:0005813centrosomeISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:94780
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:180499
Cellular ComponentGO:0005634nucleusIDAJ:94780
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:180499
Biological ProcessGO:00709353'-UTR-mediated mRNA stabilizationISOJ:164563
Biological ProcessGO:0006974cellular response to DNA damage stimulusISOJ:164563
Biological ProcessGO:0035924cellular response to vascular endothelial growth factor stimulusISOJ:164563
Biological ProcessGO:0031572G2 DNA damage checkpointISOJ:164563
Biological ProcessGO:0006954inflammatory responseIMPJ:59678
Biological ProcessGO:0048839inner ear developmentIDAJ:174607
Biological ProcessGO:0044351macropinocytosisIMPJ:126340
Biological ProcessGO:0048255mRNA stabilizationIMPJ:74321
Biological ProcessGO:0018105peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0006468protein phosphorylationIDAJ:180499
Biological ProcessGO:0032675regulation of interleukin-6 productionIMPJ:59678
Biological ProcessGO:0032680regulation of tumor necrosis factor productionIMPJ:59678
Biological ProcessGO:0032680regulation of tumor necrosis factor productionISOJ:164563
Biological ProcessGO:0034097response to cytokineISOJ:164563
Biological ProcessGO:0032496response to lipopolysaccharideIMPJ:59678
Biological ProcessGO:0032496response to lipopolysaccharideIMPJ:126340
Biological ProcessGO:0006950response to stressISOJ:164563
Biological ProcessGO:0002224toll-like receptor signaling pathwayIMPJ:126340
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
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