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GO Annotations Graph
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0008046axon guidance receptor activityIDAJ:80875
Molecular FunctionGO:0045499chemorepellent activityIBAJ:161428
Molecular FunctionGO:0035373chondroitin sulfate proteoglycan bindingISOJ:155856
Molecular FunctionGO:0043395heparan sulfate proteoglycan bindingISOJ:155856
Molecular FunctionGO:0030215semaphorin receptor bindingIPIJ:203408
Molecular FunctionGO:0045545syndecan bindingISOJ:155856
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIDAJ:80875
Cellular ComponentGO:0016020membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneIBAJ:161428
Biological ProcessGO:0048675axon extensionIGIJ:174679
Biological ProcessGO:0007411axon guidanceIMPJ:80875
Biological ProcessGO:0007413axonal fasciculationISOJ:155856
Biological ProcessGO:0002043blood vessel endothelial cell proliferation involved in sprouting angiogenesisIDAJ:203404
Biological ProcessGO:0048754branching morphogenesis of an epithelial tubeIMPJ:97663
Biological ProcessGO:0060326cell chemotaxisIDAJ:203408
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0050908detection of light stimulus involved in visual perceptionIGIJ:174679
Biological ProcessGO:0021536diencephalon developmentISOJ:155856
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:60000
Biological ProcessGO:0048843negative regulation of axon extension involved in axon guidanceIBAJ:161428
Biological ProcessGO:0048843negative regulation of axon extension involved in axon guidanceISOJ:155856
Biological ProcessGO:0007162negative regulation of cell adhesionIDAJ:203408
Biological ProcessGO:2000352negative regulation of endothelial cell apoptotic processIDAJ:203404
Biological ProcessGO:0007399nervous system developmentIEAJ:60000
Biological ProcessGO:0001755neural crest cell migrationIBAJ:161428
Biological ProcessGO:1990138neuron projection extensionIDAJ:174679
Biological ProcessGO:1990138neuron projection extensionIGIJ:174679
Biological ProcessGO:0097485neuron projection guidanceIGIJ:174679
Biological ProcessGO:0001569patterning of blood vesselsIMPJ:97663
Biological ProcessGO:0050918positive chemotaxisIDAJ:203408
Biological ProcessGO:0030836positive regulation of actin filament depolymerizationIDAJ:203404
Biological ProcessGO:0045766positive regulation of angiogenesisIDAJ:203404
Biological ProcessGO:0048842positive regulation of axon extension involved in axon guidanceISOJ:155856
Biological ProcessGO:0035413positive regulation of catenin import into nucleusIDAJ:203404
Biological ProcessGO:2001028positive regulation of endothelial cell chemotaxisIDAJ:203404
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationIDAJ:203404
Biological ProcessGO:0090091positive regulation of extracellular matrix disassemblyNASJ:203404
Biological ProcessGO:0051897positive regulation of protein kinase B signalingIDAJ:203404
Biological ProcessGO:0071526semaphorin-plexin signaling pathwayIDAJ:203408
Biological ProcessGO:1990256signal clusteringIDAJ:203408
Biological ProcessGO:1990256signal clusteringISOJ:155856

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.02
The Jackson Laboratory