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GO Annotations Graph
 Symbol
Name
ID
Npm1
nucleophosmin 1
MGI:106184

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003677DNA bindingISOJ:155856
Molecular FunctionGO:0019899enzyme bindingISOJ:155856
Molecular FunctionGO:0042393histone bindingISOJ:164563
Molecular FunctionGO:0051059NF-kappaB bindingISOJ:164563
Molecular FunctionGO:0003676nucleic acid bindingIEAJ:72247
Molecular FunctionGO:0005547phosphatidylinositol-3,4,5-trisphosphate bindingISOJ:155856
Molecular FunctionGO:0044822poly(A) RNA bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:48490
Molecular FunctionGO:0005515protein bindingIPIJ:94174
Molecular FunctionGO:0005515protein bindingIPIJ:96946
Molecular FunctionGO:0005515protein bindingIPIJ:109067
Molecular FunctionGO:0005515protein bindingIPIJ:117631
Molecular FunctionGO:0005515protein bindingIPIJ:117631
Molecular FunctionGO:0005515protein bindingIPIJ:157813
Molecular FunctionGO:0005515protein bindingIPIJ:161028
Molecular FunctionGO:0005515protein bindingIPIJ:196116
Molecular FunctionGO:0046982protein heterodimerization activityISOJ:164563
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0004860protein kinase inhibitor activityISOJ:164563
Molecular FunctionGO:0043023ribosomal large subunit bindingISOJ:142821
Molecular FunctionGO:0043024ribosomal small subunit bindingISOJ:142821
Molecular FunctionGO:0003723RNA bindingIDAJ:105455
Molecular FunctionGO:0003723RNA bindingISOJ:164563
Molecular FunctionGO:0019843rRNA bindingIDAJ:96946
Molecular FunctionGO:0019843rRNA bindingIDAJ:142821
Molecular FunctionGO:0030957Tat protein bindingISOJ:164563
Molecular FunctionGO:0003713transcription coactivator activityISOJ:164563
Molecular FunctionGO:0051082unfolded protein bindingISOJ:164563
Cellular ComponentGO:0005623cellIMPJ:142821
Cellular ComponentGO:0005813centrosomeIDAJ:103773
Cellular ComponentGO:0005813centrosomeISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:109067
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0005829cytosolIDAJ:142821
Cellular ComponentGO:0001652granular componentIDAJ:94174
Cellular ComponentGO:0005622intracellularIMPJ:142821
Cellular ComponentGO:0015934large ribosomal subunitIDAJ:142821
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0016607nuclear speckIDAJ:105455
Cellular ComponentGO:0005730nucleolusIDAJ:32712
Cellular ComponentGO:0005730nucleolusIDAJ:64959
Cellular ComponentGO:0005730nucleolusISOJ:69659
Cellular ComponentGO:0005730nucleolusISOJ:73065
Cellular ComponentGO:0005730nucleolusIDAJ:80713
Cellular ComponentGO:0005730nucleolusIDAJ:94174
Cellular ComponentGO:0005730nucleolusIDAJ:94965
Cellular ComponentGO:0005730nucleolusIDAJ:96946
Cellular ComponentGO:0005730nucleolusIDAJ:99711
Cellular ComponentGO:0005730nucleolusIDAJ:103132
Cellular ComponentGO:0005730nucleolusIDAJ:103773
Cellular ComponentGO:0005730nucleolusIDAJ:109067
Cellular ComponentGO:0005730nucleolusIDAJ:114487
Cellular ComponentGO:0005730nucleolusISOJ:117454
Cellular ComponentGO:0005730nucleolusIDAJ:130226
Cellular ComponentGO:0005730nucleolusIDAJ:142821
Cellular ComponentGO:0005730nucleolusISOJ:155856
Cellular ComponentGO:0005654nucleoplasmIDAJ:80713
Cellular ComponentGO:0005654nucleoplasmIDAJ:103773
Cellular ComponentGO:0005654nucleoplasmIDAJ:142821
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:109067
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0030529ribonucleoprotein complexISOJ:142821
Cellular ComponentGO:0015935small ribosomal subunitIDAJ:142821
Cellular ComponentGO:0031616spindle pole centrosomeISOJ:164563
Biological ProcessGO:0007569cell agingISOJ:164563
Biological ProcessGO:0016049cell growthIDAJ:142821
Biological ProcessGO:0006884cell volume homeostasisIDAJ:142821
Biological ProcessGO:0006884cell volume homeostasisIMPJ:142821
Biological ProcessGO:0007098centrosome cycleISOJ:164563
Biological ProcessGO:0006281DNA repairISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:164563
Biological ProcessGO:0008285negative regulation of cell proliferationISOJ:164563
Biological ProcessGO:0010826negative regulation of centrosome duplicationISOJ:164563
Biological ProcessGO:0048025negative regulation of mRNA splicing, via spliceosomeIDAJ:105455
Biological ProcessGO:0044387negative regulation of protein kinase activity by regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0006913nucleocytoplasmic transportIDAJ:94174
Biological ProcessGO:0006913nucleocytoplasmic transportISOJ:164563
Biological ProcessGO:0006334nucleosome assemblyISOJ:164563
Biological ProcessGO:0043085positive regulation of catalytic activityISOJ:155856
Biological ProcessGO:0008284positive regulation of cell proliferationIDAJ:142821
Biological ProcessGO:0008284positive regulation of cell proliferationIMPJ:142821
Biological ProcessGO:0031328positive regulation of cellular biosynthetic processIDAJ:142821
Biological ProcessGO:0031328positive regulation of cellular biosynthetic processIMPJ:142821
Biological ProcessGO:0010825positive regulation of centrosome duplicationIGIJ:117631
Biological ProcessGO:0051054positive regulation of DNA metabolic processISOJ:155856
Biological ProcessGO:0045740positive regulation of DNA replicationISOJ:155856
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityISOJ:164563
Biological ProcessGO:0045860positive regulation of protein kinase activityIDAJ:117631
Biological ProcessGO:0045727positive regulation of translationISOJ:164563
Biological ProcessGO:0031648protein destabilizationIMPMGI:62033
Biological ProcessGO:0051260protein homooligomerizationISOJ:155856
Biological ProcessGO:0008104protein localizationIMPJ:101353
Biological ProcessGO:0008104protein localizationISOJ:164563
Biological ProcessGO:0051259protein oligomerizationISOJ:142821
Biological ProcessGO:0051726regulation of cell cycleIMPJ:94174
Biological ProcessGO:0046599regulation of centriole replicationISOJ:164563
Biological ProcessGO:0010824regulation of centrosome duplicationIMPJ:101494
Biological ProcessGO:0043516regulation of DNA damage response, signal transduction by p53 class mediatorIGIJ:101353
Biological ProcessGO:0060735regulation of eIF2 alpha phosphorylation by dsRNAISOJ:164563
Biological ProcessGO:0032071regulation of endodeoxyribonuclease activityISOJ:164563
Biological ProcessGO:0060699regulation of endoribonuclease activityISOJ:164563
Biological ProcessGO:0043523regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:0006950response to stressISOJ:164563
Biological ProcessGO:0042273ribosomal large subunit biogenesisIMPJ:142821
Biological ProcessGO:0042273ribosomal large subunit biogenesisIDAJ:142821
Biological ProcessGO:0000055ribosomal large subunit export from nucleusIMPJ:142821
Biological ProcessGO:0042274ribosomal small subunit biogenesisIMPJ:142821
Biological ProcessGO:0042274ribosomal small subunit biogenesisIDAJ:142821
Biological ProcessGO:0000056ribosomal small subunit export from nucleusIDAJ:142821
Biological ProcessGO:0006407rRNA export from nucleusIDAJ:142821
Biological ProcessGO:0006407rRNA export from nucleusIMPJ:142821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory