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GO Annotations Graph
 Symbol
Name
ID
Pdx1
pancreatic and duodenal homeobox 1
MGI:102851

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003682chromatin bindingIDAJ:153774
Molecular FunctionGO:0001046core promoter sequence-specific DNA bindingISOJ:155856
Molecular FunctionGO:0003677DNA bindingIDAJ:80902
Molecular FunctionGO:0003677DNA bindingIDAJ:85764
Molecular FunctionGO:0003677DNA bindingIDAJ:105459
Molecular FunctionGO:0003677DNA bindingIDAJ:117676
Molecular FunctionGO:0005515protein bindingIPIJ:117676
Molecular FunctionGO:0005515protein bindingIPIJ:171241
Molecular FunctionGO:0005515protein bindingIPIJ:201256
Molecular FunctionGO:0032403protein complex bindingISOJ:155856
Molecular FunctionGO:0046982protein heterodimerization activityISOJ:155856
Molecular FunctionGO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingIDAMGI:5572886
Molecular FunctionGO:0003705contributes_to
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
ISOJ:155856
Molecular FunctionGO:0043565sequence-specific DNA bindingIDAJ:88815
Molecular FunctionGO:0043565sequence-specific DNA bindingISOJ:155856
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityIDAJ:105459
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityISOJ:155856
Molecular FunctionGO:0008134transcription factor bindingISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737colocalizes_with
cytoplasm
ISOJ:155856
Cellular ComponentGO:0005622intracellularIDAJ:105207
Cellular ComponentGO:0005622intracellularIDAJ:120581
Cellular ComponentGO:0005634nucleusIDAJ:80826
Cellular ComponentGO:0005634nucleusIDAJ:87397
Cellular ComponentGO:0005634nucleusIDAJ:99302
Cellular ComponentGO:0005634nucleusIDAJ:105459
Cellular ComponentGO:0005634nucleusIDAJ:130389
Cellular ComponentGO:0005634nucleusISOJ:155856
Biological ProcessGO:0030154cell differentiationIMPJ:104617
Biological ProcessGO:0030154cell differentiationISOJ:155856
Biological ProcessGO:0051594detection of glucoseISOJ:155856
Biological ProcessGO:0048565digestive tract developmentIMPJ:151981
Biological ProcessGO:0031018endocrine pancreas developmentIMPJ:130389
Biological ProcessGO:0031017exocrine pancreas developmentIMPJ:103522
Biological ProcessGO:0042593glucose homeostasisIMPJ:130389
Biological ProcessGO:0042593glucose homeostasisISOJ:155856
Biological ProcessGO:0042593glucose homeostasisIGIJ:165268
Biological ProcessGO:0006006glucose metabolic processIDAJ:84857
Biological ProcessGO:0030073insulin secretionISOJ:164563
Biological ProcessGO:0001889liver developmentIMPJ:151981
Biological ProcessGO:0016331morphogenesis of embryonic epitheliumIMPJ:33133
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:60000
Biological ProcessGO:0008285negative regulation of cell proliferationIMPJ:130389
Biological ProcessGO:1902236negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressIMPJ:165268
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIDAJ:117676
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedISOJ:155856
Biological ProcessGO:2000675negative regulation of type B pancreatic cell apoptotic processIMPJ:165268
Biological ProcessGO:0007263nitric oxide mediated signal transductionISOJ:164563
Biological ProcessGO:0031016pancreas developmentIMPJ:33133
Biological ProcessGO:0031016pancreas developmentIMPJ:104617
Biological ProcessGO:0010942positive regulation of cell deathISOJ:155856
Biological ProcessGO:0008284positive regulation of cell proliferationIMPJ:130389
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:155856
Biological ProcessGO:0043388positive regulation of DNA bindingISOJ:155856
Biological ProcessGO:0032024positive regulation of insulin secretionISOJ:155856
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIDAJ:88815
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIDAJ:105459
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:155856
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIDAJ:80902
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:155856
Biological ProcessGO:0042127regulation of cell proliferationIDAJ:80826
Biological ProcessGO:0006357regulation of transcription from RNA polymerase II promoterIMPJ:85764
Biological ProcessGO:0006357regulation of transcription from RNA polymerase II promoterIDAJ:88815
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:72247
Biological ProcessGO:0009749response to glucoseISOJ:155856
Biological ProcessGO:0007224smoothened signaling pathwayISOJ:155856
Biological ProcessGO:0048863stem cell differentiationISOJ:155856
Biological ProcessGO:0006366transcription from RNA polymerase II promoterISOJ:155856
Biological ProcessGO:0006351transcription, DNA-templatedISOJ:155856
Biological ProcessGO:0003309type B pancreatic cell differentiationISOJ:155856
Biological ProcessGO:0003309type B pancreatic cell differentiationISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory