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GO Annotations Graph
cofilin 1, non-muscle

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Thu Oct 8 15:06:18 2015.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003779actin bindingISOJ:155856
Cellular ComponentGO:0015629actin cytoskeletonIEAJ:72247
Cellular ComponentGO:0031252cell leading edgeISOJ:155856
Cellular ComponentGO:0042995cell projectionIEAJ:60000
Cellular ComponentGO:0005911cell-cell junctionIDAJ:205441
Cellular ComponentGO:0030864cortical actin cytoskeletonIDAJ:97332
Cellular ComponentGO:0030864cortical actin cytoskeletonIDAJ:91448
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:97332
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0005925focal adhesionISOJ:164563
Cellular ComponentGO:0005622intracellularIEAJ:72247
Cellular ComponentGO:0030027lamellipodiumISOJ:155856
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0031982vesicleISOJ:164563
Biological ProcessGO:0030042actin filament depolymerizationIEAJ:72247
Biological ProcessGO:0007015actin filament organizationIMPJ:95452
Biological ProcessGO:0030030cell projection organizationISOJ:103933
Biological ProcessGO:0007010cytoskeleton organizationISOJ:164563
Biological ProcessGO:0030010establishment of cell polarityIMPJ:95452
Biological ProcessGO:0000281mitotic cytokinesisIMPJ:97332
Biological ProcessGO:0006928movement of cell or subcellular componentIMPJ:97332
Biological ProcessGO:0045792negative regulation of cell sizeISOJ:103933
Biological ProcessGO:0001755neural crest cell migrationIMPJ:96452
Biological ProcessGO:0001842neural fold formationIMPJ:96452
Biological ProcessGO:0030836positive regulation of actin filament depolymerizationIMPJ:97332
Biological ProcessGO:0030836positive regulation of actin filament depolymerizationIDAJ:207250
Biological ProcessGO:0006606protein import into nucleusISOJ:155856
Biological ProcessGO:0006468protein phosphorylationIDAJ:116055
Biological ProcessGO:0022604regulation of cell morphogenesisISOJ:164563
Biological ProcessGO:0061001regulation of dendritic spine morphogenesisISOJ:164563
Biological ProcessGO:0043200response to amino acidIDAJ:116055

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.02
The Jackson Laboratory