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Phenotype Images associated with this Gene
Symbol
Name
ID
A1cf
APOBEC1 complementation factor
MGI:1917115


6 phenotype image(s) for A1cf alleles
Showing image(s) 1 to 6

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Caption: The Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ mouse heart is flaccid and flabby after tamoxifen induction. (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Cardiac fibrosis in Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ mouse heart (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Inhibition of dilated cardiomyopathy in Dmdtm1.1Know/Dmdtm1.1Know Tg(Myh6-2A)#Know/0 A1cfTg(Myh6-cre/Esr1*)1Jmk/0 mice (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Dmdtm1.1Know, dystrophin, muscular dystrophy; targeted mutation 1.1, Kirk Knowlton
Tg(Myh6-2A)#Know, transgene insertion, Kirk Knowlton
Copyright: This image is from Lim BK, J Clin Invest 2013 Dec 2;123(12):5146-51 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:207775
Caption: Decrease in fibrosis in Dmdtm1.1Know/Dmdtm1.1Know Tg(Myh6-2A)#Know/0 A1cfTg(Myh6-cre/Esr1*)1Jmk/0 hearts (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Dmdtm1.1Know, dystrophin, muscular dystrophy; targeted mutation 1.1, Kirk Knowlton
Tg(Myh6-2A)#Know, transgene insertion, Kirk Knowlton
Copyright: This image is from Lim BK, J Clin Invest 2013 Dec 2;123(12):5146-51 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:207775
Caption: Enlarged hearts with thinned ventricular walls and enlarged cardiac chambers in Mtortm1.1Gcon/Mtortm1.1Gcon A1cfTg(Myh6-cre/Esr1*)1Jmk/0 mice (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Mtortm1.1Gcon, mechanistic target of rapamycin kinase; targeted mutation 1.1, Gianluigi Condorelli
Copyright: This image is from Zhang D, J Clin Invest 2010 Aug 2;120(8):2805-16 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:163763
Caption: Left ventricle Mtortm1.1Gcon/Mtortm1.1Gcon A1cfTg(Myh6-cre/Esr1*)1Jmk/0 myocardium presents with sarcomeric disarray and swollen mitochondria and contains autophagic bodies after tamoxifen treatment (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Mtortm1.1Gcon, mechanistic target of rapamycin kinase; targeted mutation 1.1, Gianluigi Condorelli
Copyright: This image is from Zhang D, J Clin Invest 2010 Aug 2;120(8):2805-16 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:163763

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory