Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Six1
sine oculis-related homeobox 1
MGI:102780

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Click on allele symbol for full phenotype details.

	Caption: Perturbed myogenic differentiation of Six1^tm2.1Mair/Six1^tm2.1Mair Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ satellite cell descendants ex vivo (details) Represented Alleles: Pax7^{tm1(cre/ERT2)Gaka}, paired box 7; targeted mutation 1, Gabrielle Kardon Six1^tm2.1Mair, sine oculis-related homeobox 1; targeted mutation 2.1, Pascal Maire Copyright: This image is from Le Grand F, J Cell Biol 2012 Sep 3;198(5):815-32, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:190460
	Caption: Perturbed myogenic differentiation of Six1^tm2.1Mair/Six1^tm2.1Mair Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ satellite cell descendants ex vivo (details) Represented Alleles: Pax7^{tm1(cre/ERT2)Gaka}, paired box 7; targeted mutation 1, Gabrielle Kardon Six1^tm2.1Mair, sine oculis-related homeobox 1; targeted mutation 2.1, Pascal Maire Copyright: This image is from Le Grand F, J Cell Biol 2012 Sep 3;198(5):815-32, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:190460
	Caption: Impaired skeletal muscle regeneration in Six1^tm2.1Mair/Six1^tm2.1Mair Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ mice (details) Represented Alleles: Pax7^{tm1(cre/ERT2)Gaka}, paired box 7; targeted mutation 1, Gabrielle Kardon Six1^tm2.1Mair, sine oculis-related homeobox 1; targeted mutation 2.1, Pascal Maire Copyright: This image is from Le Grand F, J Cell Biol 2012 Sep 3;198(5):815-32, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:190460
	Caption: Impaired tissue repair in regenerated Six1^tm2.1Mair/Six1^tm2.1Mair Pax7^{tm1(cre/ERT2)Gaka}/Pax7⁺ muscles (details) Represented Alleles: Pax7^{tm1(cre/ERT2)Gaka}, paired box 7; targeted mutation 1, Gabrielle Kardon Six1^tm2.1Mair, sine oculis-related homeobox 1; targeted mutation 2.1, Pascal Maire Copyright: This image is from Le Grand F, J Cell Biol 2012 Sep 3;198(5):815-32, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:190460
	Caption: Spectrum of abnormalities of great artery patterning in mice with null mutation of one or both copies of Six1^tm1Mair and Eya1^tm1Rilm (details) Represented Alleles: Eya1^tm1Rilm, EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas Six1^tm1Mair, sine oculis-related homeobox 1; targeted mutation 1, Pascal Maire Copyright: This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023
	Caption: Increased cell death in pharyngeal endoderm Six1^tm1Mair/Six1^tm1Mair Eya1^tm1Rilm/Eya1^tm1Rilm mice (details) Represented Alleles: Eya1^tm1Rilm, EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas Six1^tm1Mair, sine oculis-related homeobox 1; targeted mutation 1, Pascal Maire Copyright: This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023
	Caption: Hypoplastic outflow tract cushions in Six1^tm1Mair/Six1^tm1Mair Eya1^tm1Rilm/Eya1^tm1Rilm mice (details) Represented Alleles: Eya1^tm1Rilm, EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas Six1^tm1Mair, sine oculis-related homeobox 1; targeted mutation 1, Pascal Maire Tbx1^tm1Bem, T-box 1; targeted mutation 1, Bernice E Morrow Copyright: This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023
	Caption: Craniofacial morphogenesis defects in mice with mutations of one or both copies of Six1^tm1Mair and Eya1^tm1Rilm (details) Represented Alleles: Eya1^tm1Rilm, EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas Six1^tm1Mair, sine oculis-related homeobox 1; targeted mutation 1, Pascal Maire Copyright: This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023
	Caption: Fgf8^tm1Moon/Fgf8⁺ Six1^tm1(cre)Xli/Six1⁺ newborns exhibit interrupted aortic arch-type B and vascular ring (details) Represented Alleles: Fgf8^tm1.3Mrt, fibroblast growth factor 8; targeted mutation 1.3, Gail R Martin Six1^tm1(cre)Xli, sine oculis-related homeobox 1; targeted mutation 1, Xue Li Copyright: This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023

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