Symbol Name ID

Six2 sine oculis-related homeobox 2 MGI:102778

10 phenotype image(s) for Six2 alleles Showing image(s) 1 to 10

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	Caption: Abnormal kidney development in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Abnormal nephron formation in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Impaired nephron induction in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: S-shaped body is reduced in size in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ nephrons (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Kidney abnormalities in Cdc42tm1Brak/Cdc42tm1Brak Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details) Represented Alleles: Cdc42tm1Brak, cell division cycle 42; targeted mutation 1, Cord Brakebusch Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Nephrogenesis abnormalities in Wwtr1tm1Hmc/Wwtr1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+, Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ and double mutant mice (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Wwtr1tm1Hmc, WW domain containing transcription regulator 1; targeted mutation 1, Helen McNeill Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Kidney development abnormalities in Cdc42tm1Brak/Cdc42tm1Brak Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details) Represented Alleles: Cdc42tm1Brak, cell division cycle 42; targeted mutation 1, Cord Brakebusch Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Hypoplasia and loss of glomeruli and proximal tubules in Wasltm2Sbs/Wasltm2Sbs Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ kidneys (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Wasltm2Sbs, WASP like actin nucleation promoting factor; targeted mutation 2, Scott B Snapper Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Loss of foot processes in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
	Caption: Decreased branching morphogenesis in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ kidneys (details) Represented Alleles: Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266