About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Prnptm3Lnq
Name: prion protein; targeted mutation 3, Susan Lindquist
MGI ID: MGI:5546407
Synonyms: CJD
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Neuropathologic processes of Prnptm3Lnq/Prnptm3Lnq micePrnptm3Lnq/Prnptm3Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Activation of cell cycle and death markers in Prnptm3Lnq/Prnptm3Lnq (B and E), and Prnptm2Lnq/Prnptm2Lnq (C and F) brainsPrnptm2Lnq/Prnptm2Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Prnptm3Lnq/Prnptm3Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Reactive gliosis in Prnptm3Lnq/Prnptm3Lnq (CJD) brain and neurodegeneration and dilated ventricles in Prnptm2Lnq/Prnptm2Lnq (FFI) brainPrnptm2Lnq/Prnptm2Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Prnptm3Lnq/Prnptm3Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Prion protein aggregates are present in the outer plexiform layer of Prnptm3Lnq/Prnptm3Lnq retinaPrnptm3Lnq/Prnptm3Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Proteinase K resistant prion protein and prion protein aggregates in Prnptm2Lnq/Prnptm2Lnq and Prnptm3Lnq/Prnptm3Lnq brainsPrnptm2Lnq/Prnptm2Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Prnptm3Lnq/Prnptm3Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Activation of cell cycle and death markers in Prnptm3Lnq/Prnptm3Lnq (CJD), and Prnptm2Lnq/Prnptm2Lnq (FFI) micePrnptm2Lnq/Prnptm2Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Prnptm3Lnq/Prnptm3Lnqinvolves: 129P2/OlaHsd * C57BL/6N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory