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Phenotype Images associated with this Allele
Nomenclature
Symbol: Sppl2atm1Basc
Name: signal peptide peptidase like 2A; targeted mutation 1, Bernd Schroder
MGI ID: MGI:5491887
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Atrophic Peyer's patches in Sppl2atm1Basc/Sppl2atm1Basc miceSppl2atm1Basc/Sppl2atm1Bascinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl
Abundant vacuoles in Sppl2atm1Basc/Sppl2atm1Basc B cellsSppl2atm1Basc/Sppl2atm1Bascinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl
Vacuoles in Sppl2atm1Basc/Sppl2atm1Basc B cells have low-electron density contentsSppl2atm1Basc/Sppl2atm1Bascinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl
Sppl2atm1Basc/Sppl2atm1Basc Cd74tm1Liz/Cd74tm1Liz B cells show normal morphology compared to the increased vacuoles in Sppl2atm1Basc/Sppl2atm1Basc B cellsSppl2atm1Basc/Sppl2atm1Bascinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl
Cd74tm1Liz/Cd74tm1Liz
Sppl2atm1Basc/Sppl2atm1Basc		B6.129-Sppl2atm1Basc Cd74tm1Liz
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory