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Phenotype Images associated with this Allele
Nomenclature
Symbol: Tsc1tm1Djk
Name: TSC complex subunit 1; targeted mutation 1, David J Kwiatkowski
MGI ID: MGI:2656240
Synonyms: Tsc1c, Tsc1fl, Tsc1flox, Tsc1L, Tsc1lox
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Brain ventricle abnormalities inTsc1tm1Djk/Tsc1tm1Djk Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+ mice injected with an adenovirus expressing cre recombinase during the neonatal periodTsc1tm1Djk/Tsc1tm1Djk
Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+		involves: 129S4/SvJae * 129S4/SvJaeSor
Hydrocephalus and enlarged pS6+ cortical cells in Tsc1tm1Djk/Tsc1tm1Djk Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+ mice injected with an adenovirus expressing cre recombinaseTsc1tm1Djk/Tsc1tm1Djk
Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+		involves: 129S4/SvJae * 129S4/SvJaeSor
Neurons above the lateral ventricles are enlarged in Tsc1tm1Djk/Tsc1tm1Djk Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+ mice injected with an adenovirus expressing cre recombinaseTsc1tm1Djk/Tsc1tm1Djk
Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+		involves: 129S4/SvJae * 129S4/SvJaeSor
Neurons above the lateral ventricles are enlarged in Tsc1tm1Djk/Tsc1tm1Djk Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+ mice injected with an adenovirus expressing cre recombinaseTsc1tm1Djk/Tsc1tm1Djk
Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+		involves: 129S4/SvJae * 129S4/SvJaeSor
Brains of Tsc1tm1Djk/Tsc1tm1Djk Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+ mice injected with an adenovirus expressing cre recombinase show ventricular region abnormalitiesTsc1tm1Djk/Tsc1tm1Djk
Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+		involves: 129S4/SvJae * 129S4/SvJaeSor
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory