Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Lpl^tm1Bres
Name:	lipoprotein lipase; targeted mutation 1, Jan L Breslow
MGI ID:	MGI:2651805
Synonyms:	L1, LPL^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Gross pathology of Lpl^tm1Bres/Lpl^tm1Bres pups at 14-16 hours after birth	Lpl^tm1Bres/Lpl^tm1Bres	involves: 129S4/SvJae * C57BL/6J
	Severe reduction of adipose tissue in Lpl^tm1Bres/Lpl^tm1Bres pups at 16 hours of age	Lpl^tm1Bres/Lpl^tm1Bres	involves: 129S4/SvJae * C57BL/6J
	Lpl^tm1Bres/Lpl^tm1Bres pups exhibit a large amount of lipids in liver sinusoids and extravasation of the lipids into the intercellular spaces	Lpl^tm1Bres/Lpl^tm1Bres	involves: 129S4/SvJae * C57BL/6J
	Skeletal muscle of Lpl^tm1Bres/Lpl^tm1Bres pups shows a reduction in perinuclear and perisarcoplasmic lipid droplets	Lpl^tm1Bres/Lpl^tm1Bres	involves: 129S4/SvJae * C57BL/6J
	Lungs of Lpl^tm1Bres/Lpl^tm1Bres pups exhibit dilated capillaries engorged with large lipoprotein particles	Lpl^tm1Bres/Lpl^tm1Bres	involves: 129S4/SvJae * C57BL/6J

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