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Phenotype Images associated with this Allele
Nomenclature
Symbol: Lpltm1Bres
Name: lipoprotein lipase; targeted mutation 1, Jan L Breslow
MGI ID: MGI:2651805
Synonyms: L1, LPL-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Gross pathology of Lpltm1Bres/Lpltm1Bres pups at 14-16 hours after birthLpltm1Bres/Lpltm1Bresinvolves: 129S4/SvJae * C57BL/6J
Severe reduction of adipose tissue in Lpltm1Bres/Lpltm1Bres pups at 16 hours of ageLpltm1Bres/Lpltm1Bresinvolves: 129S4/SvJae * C57BL/6J
Lpltm1Bres/Lpltm1Bres pups exhibit a large amount of lipids in liver sinusoids and extravasation of the lipids into the intercellular spacesLpltm1Bres/Lpltm1Bresinvolves: 129S4/SvJae * C57BL/6J
Skeletal muscle of Lpltm1Bres/Lpltm1Bres pups shows a reduction in perinuclear and perisarcoplasmic lipid dropletsLpltm1Bres/Lpltm1Bresinvolves: 129S4/SvJae * C57BL/6J
Lungs of Lpltm1Bres/Lpltm1Bres pups exhibit dilated capillaries engorged with large lipoprotein particlesLpltm1Bres/Lpltm1Bresinvolves: 129S4/SvJae * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory