Phenotype Image Detail

Image

Caption

Electron microscopy of skeletal muscle in control pup (+/+) and Lpl^tm1Bres/Lpl^tm1Bres pup (-/-) at 16 hours of age. Note the severe reduction in both perinuclear (A, +/+, x20,750; -/-. x16,500) and perisarcoplasmic (B, x8,250) lipid droplets in the mutant pups as compared with controls. L, lipid; N, nucleus; Mf, myofibrils.

Copyright

This image is from Weinstock PH, J Clin Invest 1995 Dec;96(6):2555-68 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:30062

Associated Alleles

Symbol	Name
Lpl^tm1Bres	lipoprotein lipase; targeted mutation 1, Jan L Breslow

Associated Genotypes

Allelic Composition	Genetic Background
Lpl^tm1Bres/Lpl^tm1Bres	involves: 129S4/SvJae * C57BL/6J