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Phenotype Images associated with this Allele
Nomenclature
Symbol: Pthlhtm1Hmk
Name: parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
MGI ID: MGI:2154515
Synonyms: PTHrP-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Alizarin red S stained skeletal images of hemizygous and homozygous Tg(Col2a1-PTHR1*H223R)AHju and Pthlhtm1Hmk/Pthlhtm1Hmk micePthlhtm1Hmk/Pthlhtm1Hmkinvolves: 129S2/SvPas * C57BL/6
Tg(Col2a1-PTHR1*H223R)AHju/0involves: C57BL/6
Pthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHR1*H223R)AHju/0
involves: 129S2/SvPas * C57BL/6
Histological tibiae sections of mice homozygous for Tg(Col2a1-PTHR1*H223R)AHju, mice homozygous for Tg(Col2a1-PTHR1*H223R)AHju and Pthlhtm1Hmk and mice homozygous for Pthlhtm1HmkPthlhtm1Hmk/Pthlhtm1Hmkinvolves: 129S2/SvPas * C57BL/6
Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHjuinvolves: C57BL/6
Pthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
involves: 129S2/SvPas * C57BL/6
Skeletal phenotypes and tibial histology of Pthtm1Dgo/Pthtm1Dgo, Pthlhtm1Hmk/Pthlhtm1Hmk and Pthtm1Dgo/Pthtm1Dgo Pthlhtm1Hmk/Pthlhtm1Hmk micePthtm1Dgo/Pthtm1Dgoinvolves: 129S2/SvPas * C57BL/6J
Pthtm1Dgo/Pthtm1Dgo
Pthlhtm1Hmk/Pthlhtm1Hmk
involves: 129S2/SvPas * C57BL/6J
Pthlhtm1Hmk/Pthlhtm1Hmkinvolves: 129S2/SvPas * C57BL/6J
Quantitation of bone parameters of Pthtm1Dgo/Pthtm1Dgo, Pthlhtm1Hmk/Pthlhtm1Hmk and Pthtm1Dgo/Pthtm1Dgo Pthlhtm1Hmk/Pthlhtm1Hmk micePthtm1Dgo/Pthtm1Dgoinvolves: 129S2/SvPas * C57BL/6J
Pthtm1Dgo/Pthtm1Dgo
Pthlhtm1Hmk/Pthlhtm1Hmk
involves: 129S2/SvPas * C57BL/6J
Pthlhtm1Hmk/Pthlhtm1Hmkinvolves: 129S2/SvPas * C57BL/6J
Skeletal phenotypes of wild type, Tg(Col2a1-PTHLH)2Ecw/0, Pthlhtm1Hmk/Pthlhtm1Hmk, and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 miceTg(Col2a1-PTHLH)2Ecw/0involves: C57BL/6 * SJL
Pthlhtm1Hmk/Pthlhtm1Hmkinvolves: 129S2/SvPas
Pthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Gross appearance of Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 micePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Skull comparison of wild-type and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 micePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Radiographic analysis of tooth eruption in wild-type littermates and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 micePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Tooth histology of a wild-type littermate and a Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 neonatePthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
involves: 129S2/SvPas * C57BL/6 * SJL
Dental phenotype of Pthlhtm1Hmk/Pthlhtm1Hmk mice rescued with Tg(Col2a1-PTHLH)2Ecw and Tg(PTHLH)7Wmp transgenesPthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHLH)2Ecw/0
Tg(PTHLH)7Wmp/0
involves: 129S2/SvPas * C57BL/6 * SJL

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory