Phenotype Image Detail

Image

Caption

C) Tbx1^tm6(cre)Bld/Tbx1⁺ Gt(ROSA)26Sor^{tm1(Tbx1/GFP)Bem}/Gt(ROSA)26Sor^{tm1(Tbx1/GFP)Bem} (Tbx1^Cre/+; Tbx1-GFP^flox/flox) mice show outflow tract septation (persistant truncus arteriosis, PTA) and alignment (double outlet right ventricle, DORV) defects with ventricular septal defect (VSD).

Copyright

This image is from Freyer L, BMC Dev Biol 2013 Aug 23;13(1):33, an open-access article, licensee BioMed Central Ltd. J:204435

Associated Alleles

Symbol	Name
Gt(ROSA)26Sor^tm1(Tbx1/GFP)Bem	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Bernice E Morrow
Tbx1^tm6(cre)Bld	T-box 1; targeted mutation 6, Antonio Baldini

Associated Genotypes

Allelic Composition	Genetic Background
Gt(ROSA)26Sor^tm1(Tbx1/GFP)Bem/Gt(ROSA)26Sor^tm1(Tbx1/GFP)Bem Tbx1^tm6(cre)Bld/Tbx1^+	involves: 129 * C57BL/6 * SJL