SLC6A4 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	SLC6A4	HGNC:11050 (HGNC) 6532 (Entrez Gene) 182138 (OMIM) SLC6A4 (Alliance of Genome Resources)	Chr17 q11.2	Chr17:30194319-30236002 (-) GRCh38	alcohol dependence alcohol use disorder alexithymia anxiety disorder asthma attention deficit hyperactivity disorder autistic disorder bipolar disorder chronic fatigue syndrome chronic obstructive pulmonary disease congestive heart failure dengue hemorrhagic fever depressive disorder generalized anxiety disorder heart disease liver cirrhosis major depressive disorder obsessive-compulsive disorder obstructive sleep apnea pulmonary hypertension	P31645 (UniProt \| EBI) NM_001045 (RefSeq)
mouse	Slc6a4	MGI:96285 (MGI) 15567 (Entrez Gene) Gene Tree Slc6a4 (Alliance of Genome Resources)	Chr11 46.18 cM	Chr11:76889429-76923166 (+) GRCm39	autism spectrum disorder sudden infant death syndrome	ENSMUSG00000020838 (Ensembl Gene Model) ENSMUSP00000104039 (Ensembl) ENSMUST00000108402 (Ensembl)
rat	Slc6a4	RGD:3714 (Rat Genome Database) 25553 (Entrez Gene) Slc6a4 (Alliance of Genome Resources)	Chr10 q24			P31652 (UniProt \| EBI) NM_013034 (RefSeq)
zebrafish	slc6a4a	ZDB-GENE-060314-1 (Zebrafish Model Organism Database) 664719 (Entrez Gene) slc6a4a (Alliance of Genome Resources)	Chr15			NP_001035061 (RefSeq) NM_001039972 (RefSeq)
zebrafish	slc6a4b	ZDB-GENE-060314-2 (Zebrafish Model Organism Database) 664770 (Entrez Gene) slc6a4b (Alliance of Genome Resources)	Chr5			NP_001170930 (RefSeq) NM_001177459 (RefSeq)