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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ITK HGNC:6171 (HGNC)
3702 (Entrez Gene)
186973 (OMIM)
HGNC homology
Chr5 q31-q32 Chr5:157180896-157255099 (+)
Lymphoproliferative Syndrome 1; LPFS1
Q08881 (UniProt | EBI)
NM_005546 (RefSeq)
mouse Itk MGI:96621 (MGI)
16428 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 27.75 cM Chr11:46325150-46389515 (-)
OTTMUSG00000005493 (VEGA)
OTTMUSP00000029887 (VEGA)
OTTMUST00000061071 (VEGA)
rat Itk 363577 (Entrez Gene)
Chr10 q21 NP_001102295 (RefSeq)
NM_001108825 (RefSeq)
chimpanzee ITK 735556 (Entrez Gene)
Chr5 XP_009448324 (RefSeq)
rhesus macaque ITK 715471 (Entrez Gene)
Chr6 NP_001253373 (RefSeq)
NM_001266444 (RefSeq)
cattle ITK 522311 (Entrez Gene)
Chr7 NP_001098858 (RefSeq)
NM_001105388 (RefSeq)
dog ITK 489159 (Entrez Gene)
Chr4 XP_546277 (RefSeq)
chicken ITK 416247 (Entrez Gene)
Chr13 XP_004944970 (RefSeq)
zebrafish itk 798906 (Entrez Gene)
Chr14 NP_571179 (RefSeq)
NM_131104 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory