About   Help   FAQ
Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Sdc4

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Apr 26 17:39:58 2021.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sdc4
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0001968fibronectin bindingSdc4IDARatPMID:11372670|RGD:2312328
Molecular FunctionGO:0042802identical protein bindingSDC4IPIUniProtKB:P31431HumanPMID:18093920
Molecular FunctionGO:0042802identical protein bindingSdc4IPIUniProtKB:P34901RatPMID:12571249|RGD:1580031
Molecular FunctionGO:0042802identical protein bindingSdc4IPIUniProtKB:P34901RatPMID:26601939|RGD:13825434
Molecular FunctionGO:0005546phosphatidylinositol-4,5-bisphosphate bindingsdc4IDAZfishPMID:18753130|ZFIN:ZDB-PUB-080902-19
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:P17252HumanPMID:12571249
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:O75056HumanPMID:18093920
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:P34741HumanPMID:18093920
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:Q14956HumanPMID:19350579
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:O43765HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:O43765HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:P16871HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:P21145HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:Q01453HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSDC4IPIUniProtKB:Q96EQ0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSdc4IPIUniProtKB:Q15113MouseMGI:MGI:5787767|PMID:25286301
Molecular FunctionGO:0005515protein bindingSdc4IPIUniProtKB:P04937RatPMID:10640397|RGD:8554438
Molecular FunctionGO:0005515protein bindingSdc4IPIUniProtKB:P05696RatPMID:12571249|RGD:1580031
Molecular FunctionGO:0005515protein bindingSdc4IPIUniProtKB:P34900RatPMID:26601939|RGD:13825434
Molecular FunctionGO:0005080protein kinase C bindingSdc4IDARatPMID:12571249|RGD:1580031
Molecular FunctionGO:0070053thrombospondin receptor activitySDC4IMPHumanPMID:17879962
Cellular ComponentGO:0009986cell surfaceSdc4IDAMouseMGI:MGI:3525426|PMID:15381701
Cellular ComponentGO:0009986cell surfaceSdc4IDARatPMID:10504291|RGD:2312327
Cellular ComponentGO:0043034costamereSdc4IDARatPMID:12209563|RGD:729823
Cellular ComponentGO:0070062extracellular exosomeSDC4HDAHumanPMID:19199708
Cellular ComponentGO:0005925focal adhesionSdc4IDARatPMID:12493766|RGD:1304266
Cellular ComponentGO:0005925focal adhesionsdc4IDAZfishPMID:18753130|ZFIN:ZDB-PUB-080902-19
Cellular ComponentGO:0045121membrane raftSdc4IDARatPMID:11889131|RGD:1580030
Biological ProcessGO:0007155cell adhesionsdc4IDAZfishPMID:16936286|ZFIN:ZDB-PUB-060906-8
Biological ProcessGO:0033627cell adhesion mediated by integrinsdc4IDAZfishPMID:18753130|ZFIN:ZDB-PUB-080902-19
Biological ProcessGO:0016477cell migrationsdc4IDAZfishPMID:18753130|ZFIN:ZDB-PUB-080902-19
Biological ProcessGO:0055113epiboly involved in gastrulation with mouth forming secondsdc4IMPZFIN:ZDB-MRPHLNO-120425-8ZfishPMID:22399807|ZFIN:ZDB-PUB-120314-11
Biological ProcessGO:0060122inner ear receptor cell stereocilium organizationSdc4IGIMGI:MGI:2135272MouseMGI:MGI:5498591|PMID:23760952
Biological ProcessGO:0042130negative regulation of T cell proliferationSDC4IMPHumanPMID:19350579
Biological ProcessGO:0001843neural tube closureSdc4IGIMGI:MGI:2135272MouseMGI:MGI:5498591|PMID:23760952
Biological ProcessGO:0036445neuronal stem cell divisionsdc4IMPZFIN:ZDB-MRPHLNO-120425-8ZfishPMID:27143125|ZFIN:ZDB-PUB-160505-3
Biological ProcessGO:1903543positive regulation of exosomal secretionSDC4IMPHumanPMID:22660413
Biological ProcessGO:1903553positive regulation of extracellular exosome assemblySDC4IMPHumanPMID:22660413
Biological ProcessGO:0051894positive regulation of focal adhesion assemblySdc4IMPRatPMID:10504291|RGD:2312327
Biological ProcessGO:0045860positive regulation of protein kinase activitySdc4IMPRatPMID:12571249|RGD:1580031
Biological ProcessGO:0051496positive regulation of stress fiber assemblySdc4IMPRatPMID:10504291|RGD:2312327
Biological ProcessGO:0010762regulation of fibroblast migrationSdc4IMPMouseMGI:MGI:5621257|PMID:25074804
Biological ProcessGO:0043149stress fiber assemblysdc4IDAZfishPMID:18753130|ZFIN:ZDB-PUB-080902-19
Biological ProcessGO:0001657ureteric bud developmentSdc4IEPRatPMID:15282150|RGD:1643132
Biological ProcessGO:0042060wound healingSdc4IGIMGI:MGI:2135272MouseMGI:MGI:5498591|PMID:23760952
Biological ProcessGO:0042060wound healingsdc4IDAZfishPMID:18753130|ZFIN:ZDB-PUB-080902-19

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2022
MGI 6.20
The Jackson Laboratory