Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXB8
  • Mouse genes Hoxb8
  • Rat genes Hoxb8
  • Zfish genes hoxb8a,hoxb8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxb8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Hoxb8	IDA		Mouse	MGI:MGI:5902687|PMID:15886193
Molecular Function	GO:0005515	protein binding	Hoxb8	IPI	UniProtKB:P41778	Mouse	MGI:MGI:5917381|PMID:22745600
Molecular Function	GO:0005515	protein binding	Hoxb8	IPI	UniProtKB:P41778	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0043565	sequence-specific DNA binding	Hoxb8	IMP		Mouse	MGI:MGI:5902688|PMID:11571641
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXB8	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	HOXB8	IDA		Human	GO_REF:0000052
Biological Process	GO:0008344	adult locomotory behavior	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:10559485
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96209	Mouse	PMID:11311170
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:11311170
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96183	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96190	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96186	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96198	Mouse	PMID:11311170
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96187	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IMP	MGI:MGI:2683089	Mouse	PMID:14623233
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96182	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96185	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96188	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:10559485
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb8	IGI	MGI:MGI:96184	Mouse	PMID:10885747
Biological Process	GO:0008283	cell population proliferation	hoxb8a	IMP	ZFIN:ZDB-MRPHLNO-140106-4	Zfish	PMID:24082091
Biological Process	GO:0021516	dorsal spinal cord development	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:10559485
Biological Process	GO:0021516	dorsal spinal cord development	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:18430798
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:10559485
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96188	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96184	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96185	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96183	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96190	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96186	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96187	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96182	Mouse	PMID:10885747
Biological Process	GO:0007625	grooming behavior	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:18430798
Biological Process	GO:0007625	grooming behavior	Hoxb8	IMP	MGI:MGI:2159734	Mouse	PMID:11779477
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	Hoxb8	IDA		Mouse	MGI:MGI:5447628|PMID:11438208
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hoxb8	IDA		Mouse	MGI:MGI:5902687|PMID:15886193
Biological Process	GO:0048920	posterior lateral line neuromast primordium migration	hoxb8a	IMP	ZFIN:ZDB-MRPHLNO-140106-4	Zfish	PMID:24082091
Biological Process	GO:0019233	sensory perception of pain	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:18430798
Biological Process	GO:0048705	skeletal system morphogenesis	Hoxb8	IMP	MGI:MGI:1934178	Mouse	PMID:11311170
Biological Process	GO:0048705	skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96198	Mouse	PMID:11311170
Biological Process	GO:0048705	skeletal system morphogenesis	Hoxb8	IGI	MGI:MGI:96209	Mouse	PMID:11311170

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern