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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hoxb8

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Apr 26 17:39:58 2021.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxb8
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0001227DNA-binding transcription repressor activity, RNA polymerase II-specificHoxb8IDAMouseMGI:MGI:5902687|PMID:15886193
Molecular FunctionGO:0005515protein bindingHoxb8IPIUniProtKB:P41778MouseMGI:MGI:5917381|PMID:22745600
Molecular FunctionGO:0043565sequence-specific DNA bindingHoxb8IMPMouseMGI:MGI:5902688|PMID:11571641
Molecular FunctionGO:1990837sequence-specific double-stranded DNA bindingHOXB8IDAHumanPMID:28473536
Cellular ComponentGO:0005654nucleoplasmHOXB8IDAHumanGO_REF:0000052
Biological ProcessGO:0008344adult locomotory behaviorHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:1349283|PMID:10559485
Biological ProcessGO:0009952anterior/posterior pattern specificationHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:1349283|PMID:10559485
Biological ProcessGO:0009952anterior/posterior pattern specificationHoxb8IGIMGI:MGI:96183|MGI:MGI:96184|MGI:MGI:96185|MGI:MGI:96186|MGI:MGI:96187|MGI:MGI:96188|MGI:MGI:96182|MGI:MGI:96190MouseMGI:MGI:1859107|PMID:10885747
Biological ProcessGO:0009952anterior/posterior pattern specificationHoxb8IMPMGI:MGI:2683089MouseMGI:MGI:2681074|PMID:14623233
Biological ProcessGO:0009952anterior/posterior pattern specificationHoxb8IGIMGI:MGI:96198|MGI:MGI:96209MouseMGI:MGI:1933164|PMID:11311170
Biological ProcessGO:0009952anterior/posterior pattern specificationHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:1933164|PMID:11311170
Biological ProcessGO:0008283cell population proliferationhoxb8aIMPZFIN:ZDB-MRPHLNO-140106-4ZfishPMID:24082091|ZFIN:ZDB-PUB-131105-7
Biological ProcessGO:0021516dorsal spinal cord developmentHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:1349283|PMID:10559485
Biological ProcessGO:0021516dorsal spinal cord developmentHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:3789512|PMID:18430798
Biological ProcessGO:0048704embryonic skeletal system morphogenesisHoxb8IGIMGI:MGI:96183|MGI:MGI:96184|MGI:MGI:96185|MGI:MGI:96186|MGI:MGI:96187|MGI:MGI:96188|MGI:MGI:96182|MGI:MGI:96190MouseMGI:MGI:1859107|PMID:10885747
Biological ProcessGO:0048704embryonic skeletal system morphogenesisHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:1349283|PMID:10559485
Biological ProcessGO:0007625grooming behaviorHoxb8IMPMGI:MGI:2159734MouseMGI:MGI:2156345|PMID:11779477
Biological ProcessGO:0007625grooming behaviorHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:3789512|PMID:18430798
Biological ProcessGO:0045638negative regulation of myeloid cell differentiationHoxb8IDAMouseMGI:MGI:5447628|PMID:11438208
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIHoxb8IDAMouseMGI:MGI:5902687|PMID:15886193
Biological ProcessGO:0048920posterior lateral line neuromast primordium migrationhoxb8aIMPZFIN:ZDB-MRPHLNO-140106-4ZfishPMID:24082091|ZFIN:ZDB-PUB-131105-7
Biological ProcessGO:0019233sensory perception of painHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:3789512|PMID:18430798
Biological ProcessGO:0048705skeletal system morphogenesisHoxb8IGIMGI:MGI:96198MouseMGI:MGI:1933164|PMID:11311170
Biological ProcessGO:0048705skeletal system morphogenesisHoxb8IGIMGI:MGI:96209MouseMGI:MGI:1933164|PMID:11311170
Biological ProcessGO:0048705skeletal system morphogenesisHoxb8IMPMGI:MGI:1934178MouseMGI:MGI:1933164|PMID:11311170

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory