Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPLX1
  • Mouse genes Cplx1
  • Rat genes Cplx1
  • Zfish genes cplx2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cplx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	Cplx1	IMP		Mouse	MGI:MGI:3688343|PMID:15126625
Molecular Function	GO:0005515	protein binding	CPLX1	IPI	UniProtKB:P60880-2	Human	PMID:21785412
Molecular Function	GO:0005515	protein binding	CPLX1	IPI	UniProtKB:P60880-2	Human	PMID:21785414
Molecular Function	GO:0000149	SNARE binding	Cplx1	IDA		Rat	PMID:11751907|RGD:727333
Molecular Function	GO:0000149	SNARE binding	Cplx1	IDA		Rat	PMID:18201107|RGD:2311133
Molecular Function	GO:0000149	SNARE binding	Cplx1	IDA		Rat	PMID:19255244|RGD:2311128
Molecular Function	GO:0017075	syntaxin-1 binding	Cplx1	IDA		Rat	PMID:7553862|RGD:70701
Cellular Component	GO:0044305	calyx of Held	Cplx1	IDA		Mouse	PMID:26019341
Cellular Component	GO:0030425	dendrite	Cplx1	IDA		Rat	PMID:7553862|RGD:70701
Cellular Component	GO:0098978	glutamatergic synapse	Cplx1	IDA		Mouse	PMID:11163241
Cellular Component	GO:0098978	glutamatergic synapse	Cplx1	IMP		Mouse	PMID:11163241
Cellular Component	GO:0098978	glutamatergic synapse	Cplx1	IMP		Mouse	PMID:22284181
Cellular Component	GO:0098978	glutamatergic synapse	Cplx1	IDA		Mouse	PMID:22284181
Cellular Component	GO:0043025	neuronal cell body	Cplx1	IDA		Rat	PMID:7553862|RGD:70701
Cellular Component	GO:0098794	postsynapse	Cplx1	IDA		Mouse	PMID:26019341
Cellular Component	GO:0098794	postsynapse	Cplx1	IDA		Rat	PMID:10430466|RGD:13702170
Cellular Component	GO:0098793	presynapse	Cplx1	IDA		Mouse	PMID:26019341
Cellular Component	GO:0098793	presynapse	Cplx1	IDA		Rat	PMID:10430466|RGD:13702170
Cellular Component	GO:0032991	protein-containing complex	Cplx1	IDA		Rat	PMID:19255244|RGD:2311128
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cplx1	IDA		Mouse	PMID:22284181
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Cplx1	IMP		Mouse	PMID:22284181
Cellular Component	GO:0031201	SNARE complex	Cplx1	IDA		Mouse	MGI:MGI:3688343|PMID:15126625
Cellular Component	GO:0045202	synapse	Cplx1	IDA		Rat	PMID:7553862|RGD:70701
Cellular Component	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex	Cplx1	IDA		Rat	PMID:7553862|RGD:70701
Cellular Component	GO:0043195	terminal bouton	Cplx1	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0030073	insulin secretion	Cplx1	IMP		Mouse	MGI:MGI:3688343|PMID:15126625
Biological Process	GO:0099145	regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Cplx1	IDA		Mouse	PMID:22284181
Biological Process	GO:0099145	regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Cplx1	IMP		Mouse	PMID:22284181
Biological Process	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Cplx1	IDA		Mouse	PMID:11163241
Biological Process	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Cplx1	IMP		Mouse	PMID:11163241
Biological Process	GO:0016079	synaptic vesicle exocytosis	Cplx1	IMP		Mouse	MGI:MGI:3688343|PMID:15126625
Biological Process	GO:0016079	synaptic vesicle exocytosis	Cplx1	IDA		Rat	PMID:11751907|RGD:727333

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern