Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including cAMP-mediated signaling; cellular response to cAMP; and nervous system development. Predicted to be located in several cellular components, including bicellular tight junction; late endosome; and neuronal cell body. Predicted to be part of protein-containing complex. Predicted to be active in apical plasma membrane and endocytic vesicle. Is expressed in embryo; olfactory epithelium; yolk sac endoderm; and yolk sac mesenchyme. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 7. Orthologous to human RAPGEF2 (Rap guanine nucleotide exchange factor 2).