Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have SH3 domain binding activity; receptor tyrosine kinase binding activity; and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of T cell anergy; positive regulation of protein metabolic process; and regulation of signal transduction. Predicted to localize to several cellular components, including cytosol; membrane raft; and nucleoplasm. Is expressed in brain; extrinsic ocular muscle; and incisor. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human CBLB (Cbl proto-oncogene B).