Automated description from the Alliance of Genome Resources
Exhibits guanyl-nucleotide exchange factor activity. Involved in several processes, including immunological synapse formation; positive regulation of T cell migration; and positive regulation of establishment of T cell polarity. Localizes to the cell leading edge. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 2. Is expressed in central nervous system; retina; and thymus primordium. Orthologous to human DOCK8 (dedicator of cytokinesis 8).